Eli Lilly

Greater Gift brings clinical trial awareness through Hero’s Journey art project

Monday, November 6, 2017

Winston-Salem, North Carolina, will be one of only three cities across the nation to host a Hero’s Journey Art sculpture when it is unveiled next month at the Benton Convention Center. Greater Gift, a Winston-Salem non-profit with a mission to highlight the impact of clinical trial research, has partnered with Eli Lilly to honor clinical trial participants through the commissioning of three art pieces, by artist John Magnan, which will be displayed in Winston-Salem, Austin, Texas and Indianapolis, Indiana.

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Eli Lilly’s Verzenio grabs Priority Review for advanced breast cancer

Friday, October 13, 2017

Eli Lilly announced that the FDA has granted Priority Review designation for its New Drug Application (NDA) for Verzenio (abemaciclib), a cyclin-dependent kinase (CDK)4 & 6 inhibitor. The NDA was based upon the positive interim results from MONARCH 3, a study of abemaciclib in combination with an aromatase inhibitor as initial endocrine-based therapy for the treatment of women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.

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Lilly closes two R&D centers, cuts 3,500 jobs

Friday, September 8, 2017

Eli Lilly announced actions to streamline operations to more efficiently focus resources on developing new medicines and to improve its cost structure. Global workforce reductions, including those from a U.S. voluntary early retirement program, are expected to impact approximately 3,500 positions.

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Topas Therapeutics, Eli Lilly ink agreement on immune tolerance

Friday, August 25, 2017

Topas Therapeutics, a Hamburg, Germany-based private company, has signed a multi-year agreement with Eli Lilly to collaborate in the field of antigen-specific tolerance induction with an initial focus on external antigens thought to induce inflammation and/or autoimmune disease. Topas will be responsible for conducting pre-clinical proof-of-principle studies in collaboration with Lilly to generate drug candidates. Under the terms of the agreement, Lilly has an option for all candidates produced under the collaboration for in-licensing and further development. Topas will receive R&D funding and participate in the future success of any compounds in-licensed by Lilly. Financial details of the collaboration are not being disclosed.

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Adimab announces platform transfer with Lilly

Friday, July 21, 2017

Adimab, a global leader in the discovery and optimization of fully human monoclonal and bispecific antibodies, has entered into an agreement with Eli Lilly to transfer the Adimab Platform to Lilly for the discovery and optimization of antibody-based drugs in all therapeutic areas. This technology transfer expands an ongoing collaboration between the two companies that was initiated in 2010, which has yielded several undisclosed therapeutic candidates for Lilly.

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Revisiting patient diversity in clinical trials… again

Saturday, July 1, 2017

Minority groups have historically been excluded from clinical research, an inequity that has led to well-documented public health problems in which therapies tested primarily in Caucasian patients do not work as well in other ethnic and racial groups. This problem is famously exemplified by Sanofi’s blood thinner Plavix, which was approved in 1997 but slapped with a boxed warning in 2010 after researchers realized up to half of Asian and Pacific Islander populations cannot process the drug.

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Pfizer and Lilly receive FDA Fast Track designation for Tanezumab

Tuesday, June 13, 2017

Pfizer and Eli Lilly announced that the FDA has granted Fast Track designation for tanezumab for the treatment of chronic pain in patients with osteoarthritis (OA) and chronic low back pain (CLBP). Tanezumab is an investigational humanized monoclonal antibody that selectively targets, binds to and inhibits nerve growth factor (NGF). It is the first NGF inhibitor to receive Fast Track designation, a process designed to facilitate the development and expedite the review of new therapies to treat serious conditions and fill unmet medical needs.

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