Schepens Eye Research Institute

VGX-100 identified as potential therapy for improving corneal graft survival

Monday, January 30, 2012 02:40 PM

Circadian Technologies has published data in Investigative Ophthalmology & Visual Science (IOVS) showing that VEGF-C expression is markedly up-regulated in corneal graft rejection. The data also showed that VEGF-C blockade, through administration of Circadian's lead development candidate VGX-100, a human antibody against VEGF-C, significantly improved corneal graft survival in an animal model. The data indicates a new therapeutic opportunity for VGX-100 to improve corneal graft survival.

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Mass. Eye and Ear, Schepens Eye Research merging

Friday, June 10, 2011 12:17 PM

The Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute are combining forces to create the world's largest basic and clinical ophthalmology research enterprise, with full spectrum bench-to-bedside research that will translate more quickly into better treatment for blinding diseases and, ultimately, cures.

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December 17

Medici Global says its Alzheimer's Facebook page demonstrates the need for more early detection trials

Analysts: Expect more equity purchases of CROs in 2013

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January 2013

Parexel celebrates 30 years of change, growth
CRO's founder and chairman reflects on challenges of the past, present and future

Strategies for increasing patient diversity in trials
Sponsors look to improve racial, ethnic recruitment without going overseas

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December 2012

Publicity, regulation tightening reins on use of KOLs
Debate rages over need to revamp how sponsors use, pay medical experts

Time may be right to makeover the investigator brochure
Size, complexity prevent critical document from being thoroughly read

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