Global News

X-Chem, Vertex enter genetic disease collaboration

Wednesday, May 17, 2017

X-Chem, a privately held biotechnology company applying its innovative drug discovery platform to the generation of novel small molecule therapeutics, announced a collaboration with Vertex Pharmaceuticals. X-Chem will apply its proprietary DEXTM libraries, which contain more than 120 billion small molecules, toward the discovery of new drug leads against targets involved in multiple specialty diseases. Vertex will have the option to license lead-like hits discovered under the collaboration, and will be responsible for further development and commercialization of the resulting programs.

[Read More]

Charles River Laboratories updates oncology business

Wednesday, May 17, 2017

Charles River Laboratories International recently announced updates to its expanding oncology discovery business, including significant additions to its online Tumor Model Compendium. The Compendium provides oncology researchers with a resource to identify and locate targeted suitable patient-derived xenografts (PDXs) based on specific histology and molecular properties, and now includes additional molecular characteristics for syngeneic models.

[Read More]

Rady Children’s Institute, Alexion partner on genetic disorders

Wednesday, May 17, 2017

The Rady Children’s Institute for Genomic Medicine (RCIGM) and Alexion Pharmaceuticals announced a strategic partnership to accelerate the diagnosis of critically ill newborns with rare genetic disorders. The collaboration combines the Institute’s genomic research expertise with Alexion data science and bioinformatics capabilities to advance precision medicine for infants in an intensive care setting.

[Read More]

Bracket launches cloud-based version of SmartSupplies

Tuesday, May 16, 2017

Bracket, a clinical trial technology and specialty services provider, launched a cloud-based service for SmartSupplies, its clinical trial inventory management software suite. This launch marks the first hosted solution of SmartSupplies since Bracket’s acquisition of CLINapps in 2016 and is applicable to all modules of the SmartSupplies suite.

[Read More]

Synlogic and Mirna Therapeutics to merge

Tuesday, May 16, 2017

Privately held Synlogic has entered into a definitive merger agreement with Mirna Therapeutics under which Synlogic will merge with a wholly owned subsidiary of Mirna in an all-stock transaction. The merged company will continue under the Synlogic name and will focus on advancing Synlogic’s drug discovery and development platform for Synthetic Biotic medicines, which are designed using synthetic biology to genetically reprogram beneficial microbes to treat metabolic and inflammatory diseases and cancer.

[Read More]

Thermo Fisher Scientific to acquire Patheon

Tuesday, May 16, 2017

Thermo Fisher Scientific will acquire Patheon, a global provider of high-quality drug development and delivery solutions to the pharmaceutical and biopharma sectors. Thermo Fisher will commence a tender offer to acquire all of the issued and outstanding shares of Patheon for $35 per share in cash. The transaction represents a purchase price of approximately $7.2 billion, which includes the assumption of approximately $2 billion of net debt.

[Read More]