Drug Sponsors

AstraZeneca acquires ZS Pharma

Monday, November 9, 2015

AstraZeneca has entered into a definitive agreement to acquire ZS Pharma, a biopharmaceutical company based in San Mateo, Calif. ZS Pharma uses its proprietary ion-trap technology to develop novel treatments for hyperkalaemia (high potassium levels), a serious condition of elevated potassium in the bloodstream, typically associated with chronic kidney disease (CKD) and chronic heart failure (CHF).

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KaloBios to reduce workforce by 61%

Monday, November 9, 2015

KaloBios Pharmaceuticals, based in South San Francisco, Calif., will reduce its workforce as part of a plan to reduce operating costs. The action will reduce the company’s workforce by about 17 employees (or 61%), and will focus the company’s resources on the ongoing development of lenzilumab, also known as KB003, in chronic monomyelocytic leukemia (CMML), while it continues to pursue strategic alternatives for the company.

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Mylan cleared by FTC to acquire Perrigo

Thursday, November 5, 2015

Mylan has announced the U.S. Federal Trade Commission (FTC) has cleared the company’s proposed transaction to acquire Perrigo subject to Mylan’s divestiture of certain products following the consummation of the offer. The FTC clearance represents the final regulatory clearance needed by Mylan to close its acquisition of Perrigo and represents the last remaining condition that needs to be satisfied for the successful completion of the offer other than the acceptance condition.

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Dimension Therapeutics expands internal R&D

Thursday, November 5, 2015

Dimension Therapeutics, a gene therapy company advancing novel, liver-directed treatments for diverse rare diseases, plans to expand the company’s internal research and process development capabilities. Dimension has signed a lease agreement with Alexandria Real Estate Equities, for 17,475 square feet of state-of-the-art laboratory and office space at 19 Presidential Way in Woburn, Mass., with occupancy expected in April 2016. The expansion builds upon Dimension’s existing mammalian cell platform in Cambridge, and will support continued innovation in vector optimization and development of manufacturing processes required for IND-enabling studies and the reliable production of high-quality AAV vectors at commercial scale.

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Bristol-Myers Squibb to acquire Cardioxyl

Monday, November 2, 2015

Bristol-Myers Squibb will acquire all of the issued and outstanding capital stock of Chapel Hill, N.C.-based Cardioxyl Pharmaceuticals, a private biotechnology company focused on cardiovascular disease. The acquisition will give Bristol-Myers Squibb full rights to Cardioxyl’s lead asset CXL-1427, a novel nitroxyl (HNO) donor (prodrug) in phase II clinical development as an intravenous treatment for acute decompensated heart failure (ADHF).

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