Clinical Intelligence

Positive results for Newron phase II study of evenamide for schizophrenia

Wednesday, April 6, 2016

Newron Pharmaceuticals, an Italy-based biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain, has presented results for Evenamide (NW-3509), a putative antipsychotic that targets abnormal electrical activity and glutamatergic abnormalities in improving psychotic symptoms in patients with schizophrenia, in a phase II, placebo-controlled trial.

[Read More]

Genocea releases positive results for genital herpes treatment GEN-003

Tuesday, April 5, 2016

Genocea Biosciences, a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, has announced positive 12 month efficacy data from its phase II dose optimization trial evaluating GEN-003 for the treatment of genital herpes. GEN-003 demonstrated sustained and statistically significant reductions compared to baseline in the rate of viral shedding 12 months after dosing across multiple dose groups as well as sustained efficacy at multiple dose levels across secondary endpoints measuring the impact on clinical disease. GEN-003 was safe and well-tolerated by patients, with no serious adverse events related to the vaccine in the trial.

[Read More]

Lilly’s Taltz (ixekizumab) receives FDA approval for plaque psoriasis

Friday, March 25, 2016

The FDA has approved Eli Lilly’s Taltz (ixekizumab) injection 80mg/mL for the treatment of moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy. Taltz should not be used in patients with a previous hypersensitivity reaction, such as anaphylaxis, to ixekizumab or to any of the excipients. Taltz is designed to specifically target IL-17A, a protein that plays a role in driving underlying inflammation in psoriasis.

[Read More]