R&D Trends

EMD Millipore inks agreement with Precision Biologics

Monday, February 2, 2015 02:00 PM

EMD Millipore, the life science business of Merck of Darmstadt, Germany, has announced an agreement for providing upstream process development services for Precision Biologics, a Texas-based clinical-stage biotechnology company, to advance a preclinical monoclonal antibody. The antibody, NEO-201, binds to a tumor-specific antigen found in several forms of cancer, offering therapeutic potential across multiple cancer types, including colorectal, lung, ovarian and pancreatic, an especially deadly cancer with limited treatment options.

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AstraZeneca, MD Anderson collaborate for ovarian/gynecologic cancers

Monday, February 2, 2015 01:50 PM

AstraZeneca and the University of Texas MD Anderson Cancer Center have announced a multi-year, strategic research collaboration to conduct multiple, parallel clinical and clinically-related studies in ovarian and other gynecologic cancers with the aim of improving patient outcomes.

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U.K. announces $21M investment in stratified medicine

Friday, January 30, 2015 12:29 PM

Minister for Life Sciences George Freeman has announced a further $20.6 million investment in stratified medicine collaborations funded by the Medical Research Council (MRC). Four new awards bring the total of stratified medicine consortia funded by the MRC to 13, with investments totaling over $21 million—part of the government’s $195.4 million commitment to stratified medicine set out in the U.K. life sciences strategy.

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Astellas Pharma, Immunomic Therapeutics collaborate

Friday, January 30, 2015 12:25 PM

Immunomic Therapeutics, a company developing next-generation vaccines based on the LAMP-vax platform headquartered in Hershey, Pa., and Astellas Pharma of Tokyo have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen. The companies expect to initiate a phase I trial of JRC2-LAMP-vax in Japan as soon as it is ready.

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Sigma-Aldrich, VIB ink alliance on novel translational research tools

Friday, January 23, 2015 11:46 AM

Sigma-Aldrich's research business unit, which supports translational researchers by supplying the products, services and solutions needed to enable scientific discovery, has formed an alliance with VIB, a life science research institute based in Flanders, Belgium, focused on translational research in medical, agricultural and industrial applications. The alliance will focus on the commercialization and supply of new tools and technologies to help meet the evolving needs of translational researchers.

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Array to acquire Novartis BRAF inhibitor encorafenib (LGX818)

Friday, January 23, 2015 11:40 AM

Array BioPharma, based in Boulder, Colo., has reached a definitive agreement with Novartis Pharma to acquire worldwide rights to encorafenib (LGX818), a BRAF inhibitor currently in phase III development. This agreement is conditional on the closing of transactions announced by Novartis and GlaxoSmithKline on April 22, 2014, which are expected to close in the first half of 2015, and the agreement remains subject to the receipt of regulatory approvals.

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Curis, Aurigene collaborate for immuno-oncology and precision oncology targets

Thursday, January 22, 2015 12:14 PM

Curis, a Lexington, Mass.-based biotechnology company focused on the development and commercialization of innovative drug candidates for the treatment of human cancers, and Aurigene Discovery Technologies, a Bangalore, India-based, specialized, discovery stage biotechnology company developing novel therapies to treat cancer and inflammatory diseases, have entered into an exclusive collaboration agreement focused on immuno-oncology and selected precision oncology targets.

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Zymeworks, Celgene collaborate

Thursday, January 22, 2015 12:12 PM

Zymeworks, a privately held biotherapeutics company based in Vancouver, has formed a collaboration and licensing agreement with Celgene for the research, development and commercialization of bi-specific antibody therapeutics enabled using Zymeworks’ proprietary Azymetric platform.

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Report: Midwest healthcare companies raise $1.8B in 2014

Wednesday, January 21, 2015 01:06 PM

Midwest healthcare companies attracted $1.8 billion in new investments across 243 companies in 2014, according to the BioEnterprise Midwest Healthcare Growth Capital Report. The totals are the highest recorded in both dollars and number of companies funded since BioEnterprise began compiling the report in 2005, surpassing the banner 2007 by 46% and 2013 by 135%. BioEnterprise is a business formation, recruitment, and acceleration initiative designed to grow healthcare companies and commercialize bioscience technologies based in Cleveland, Ohio.

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BioInvent inks agreement with Cancer Research U.K., CRT and LLR

Wednesday, January 21, 2015 01:02 PM

BioInvent International, a research-based pharmaceutical company based in Sweden, has reached an agreement with Cancer Research U.K.Cancer Research Technology (CRT), the charity’s development and commercialization arm, and Leukemia & Lymphoma Research (LLR) to take its investigational drug, BI-1206, into a collaborative phase I/II trial for patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).

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CenterWatch
CWWeekly

February 23

Venture capital investors funding novel drug R&D three times more than companies repurposing, improving existing drugs

In appreciation: Karen Woodin will be remembered for her teaching, writing and lasting friendships

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The CenterWatch Monthly

February

Study grants market breaks $13 billion
Volume of clinical activity rising while growth in grant spending slows

Revisiting eClinical Technology Solutions Adoption
While use of established solutions grows, sponsors hesitate on newer tools

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The CenterWatch Monthly

January

All eyes on EMA’s adaptive licensing pilot
Sponsors could offer innovative drugs to patients 8 years sooner

Ice Bucket Challenge a boon for ALS research
Donations soar, but phenomenon difficult to replicate

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