Theorem Clinical Research

R&D Trends

Novartis provides drug candidate compounds to TB Alliance

Thursday, August 21, 2014 01:48 PM

Novartis has signed an exclusive worldwide licensing agreement with the Global Alliance for TB Drug Development (TB Alliance), which has locations in the U.S., Brussels and South Africa, for compounds to fight tuberculosis (TB) that have been discovered at the Novartis Institutes for Tropical Diseases (NITD).

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AstraZeneca, Mitsubishi Tanabe Pharma collaborate on diabetic nephropathy

Thursday, August 21, 2014 01:45 PM

AstraZeneca and Mitsubishi Tanabe Pharma Corporation (MTPC), a research-driven pharmaceutical company based in Japan, have announced a three-year research collaboration in diabetic nephropathy. The aim is to leverage complementary strengths, expertise and assets to validate and progress novel research targets and molecules into clinical development.

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Bristol-Myers Squibb, Celgene collaborate on combination regimen

Thursday, August 21, 2014 01:44 PM

Bristol-Myers Squibb and Celgene have established a clinical trial collaboration to evaluate the safety, tolerability and preliminary efficacy of a combination regimen of BMS’ investigational PD-1 immune checkpoint inhibitor, Opdivo (nivolumab), and Celgene’s nab technology-based chemotherapy Abraxane (paclitaxel protein-bound particles for injectable suspension) (albumin-bound), in a phase I study.

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Illumina partners with AstraZeneca, Janssen, Sanofi for oncology

Thursday, August 21, 2014 01:42 PM

Illumina, a California-based developer, manufacturer and marketer of life science tools and integrated systems for the analysis of genetic variation and function, has formed collaborative partnerships with AstraZenecaJanssen Biotech and Sanofi to develop a universal next-generation sequencing (NGS)-based oncology test system.

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BARDA extends contract with Cytori for thermal burn treatment

Wednesday, August 20, 2014 01:29 PM

Cytori Therapeutics, a California-based developer of cell therapies based on autologous adipose-derived regenerative cells (ADRCs) to treat cardiovascular disease and other medical conditions, and Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services, have announced the execution of a contract option to fund the continued investigation and development of Cytori Cell Therapy for use in thermal burn injuries.

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RTI International develops novel lung-on-a-chip

Wednesday, August 20, 2014 01:27 PM

Researchers at RTI International, a nonprofit organization headquartered in Research Triangle Park, N.C., that provides research and technical services, in collaboration with the University of North Carolina at Chapel Hill, have developed a new lung-on-chip microdevice for laboratory studies of respiratory challenges and therapeutics. The microdevice includes multiple vertically stacked cellular layers that mimic the structure of the airway tissue. 

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Roche, Garvan Institute of Medical Research partner

Wednesday, August 20, 2014 01:22 PM

Roche and the Australia-based Garvan Institute of Medical Research are collaborating to develop new technologies for targeted epigenomic analysis using DNA sequencing. Genomics is a rapidly evolving field with a focus on realizing the potential use of sequencing information in patient diagnosis and treatment.

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A*STAR, Sumitomo Mitsui Banking ink MOU for Japanese R&D in Singapore

Wednesday, August 20, 2014 01:19 PM

The Singapore-based Agency for Science, Technology and Research (A*STAR) and Japan-based Sumitomo Mitsui Banking Corporation (SMBC) have inked a memorandum of understanding (MOU), with the aim of supporting Japanese R&D activities in Singapore for the next three years.

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MD Anderson, Foundation Medicine partner

Friday, August 15, 2014 02:52 PM

The University of TexasMD Anderson Cancer Center has announced an alliance with Cambridge, Mass.-based Foundation Medicine. The teams are opening a randomized, controlled trial to determine whether targeted therapies selected based on tumor molecular profiling compared with treatment not selected on this basis results in longer progression-free survival in patients with advanced disease.

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Biocryst Pharmaceuticals receives NIAID funds for hemorrhagic fever viruses

Thursday, August 14, 2014 11:44 AM

BioCryst Pharmaceuticals, based in Research Triangle Park, N.C., has announced the National Institute of Allergy and Infectious Diseases (NIAID) has exercised additional options to conduct phase I clinical human safety trials of an intramuscular formulation of BCX4430.

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