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R&D Trends

Second Genome, Mayo Clinic collaborate to develop microbiome therapeutics

Thursday, October 9, 2014 09:00 AM

Second Genome, a South San Francisco, Calif.-based developer of novel medicines through innovative microbiome science, has entered into an extensive partnership with the Minnesota-based Mayo Clinic Center for Individualized Medicine to support the development of therapeutic products for multiple disease indications, starting with inflammatory bowel disease, metabolic disorders and colorectal cancer.

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NanoString, Brigham and Women's Hospital collaborate

Thursday, October 9, 2014 08:30 AM

NanoString Technologies, a Seattle, Wash.-based provider of life science tools for translational research and molecular diagnostic products, has signed a multi-year, multi-investigator research collaboration with Harvard-affiliated, Boston, Mass.-based Brigham and Women's Hospital (BWH) to accelerate the translation of genomic biomarker discoveries into clinical cancer diagnostics. Using NanoString's Elements reagents, assays will be developed to detect gene expression, copy number variations and fusions from a diverse range of tumor samples.

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CenterWatch

Survey: Global medtech industry needs to better differentiate products

Wednesday, October 8, 2014 01:53 PM

Despite ongoing commercial challenges in 2013, the global medtech industry's financial performance held steady at the relatively low levels of growth that have become common in recent years. But even as the industry grapples with these market and regulatory pressures, it faces a potential growing challenge—the threat of commoditization, according to new findings outlined in Ernst & Young's annual medical technology report, Pulseof the industry: differentiating differently.

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Merck Serono to collaborate with Institute of Cancer Research, Wellcome Trust

Wednesday, October 8, 2014 01:42 PM

Merck Serono, the Germany-based biopharmaceutical division of Merck; the London-based Institute of Cancer Research (ICR); and the Wellcome Trust, a U.K. charitable foundation, have announced a co-development and license agreement building on two independent research programs at both the ICR and Merck Serono to identify inhibitors of tankyrase, an enzyme of the poly (ADP-ribose) polymerase family.

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Report: Past drug failures vital to drug development process

Wednesday, October 8, 2014 01:36 PM

A number of investigational cancer medicines that did not succeed in clinical trials, so-called "failures," are a critical part of the drug development process, according to a report by the Wash. D.C.-based Pharmaceutical Research and Manufacturers of America (PhRMA).

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Epirus, Livzon Mabpharm collaborate in China

Wednesday, October 8, 2014 12:00 PM

Epirus Biopharmaceuticals, a Boston-based biopharmaceutical company focused on the global development and commercialization of biosimilar monoclonal antibodies, has signed a royalty-bearing, multi-product collaboration agreement with Livzon Mabpharm, a Chinese biotechnology company focused on the development, manufacture and sale of antibody-based drugs.

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Tenax Therapeutics halts phase IIb trial

Tuesday, October 7, 2014 01:00 PM

Tenax Therapeutics, formerly named Oxygen Biotherapeutics, a Morrisville, N.C.-based specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical care market, has announced that the company, with unanimous approval from the board of directors, has elected to stop the current phase IIb trial for its Oxycyte drug candidate and consider strategic alternatives for the program moving forward. The company will review the data generated on the patients enrolled in the trial to date.

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HUYA Bioscience International, Tianjin Institute of Pharmaceutical Research partner

Tuesday, October 7, 2014 09:30 AM

HUYA Bioscience International, an accelerator of the global development of China’s pharmaceutical innovations, has announced a joint venture with Tianjin Institute of Pharmaceutical Research (TIPR) to develop medical technologies and therapies, originating in both China and the western world, for global markets.

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John O´Keefe, May-Britt Moser, Edvard I. Moser win Nobel prize

Monday, October 6, 2014 03:36 PM

The Nobel Assembly at Karolinska Institute has awarded the 2014 Nobel Prize in Physiology or Medicine to John O´Keefe and jointly to May-Britt Moser and Edvard I. Moser for their discoveries of cells that constitute a positioning system in the brain.

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DIA, Korea National Enterprise for Clinical Trials ink MoU

Friday, October 3, 2014 11:02 AM

Korea National Enterprise for Clinical Trials (KoNECT) and DIA (Drug Information Association), based in Washington, D.C., have signed a Memorandum of Understanding (MoU) to establish a cooperative relationship and explore collaboration in development of training, education and knowledge exchange opportunities.

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CWWeekly

November 24

Tufts CSDD’s $2.6 billion price tag to develop and bring a new drug to market raises questions, criticisms

Medidata joins GlaxoSmithKline in study to evaluate the impact of wearing mobile devices in clinical trials

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The CenterWatch Monthly

November

Private equity driving dynamic CRO growth
Enables CROs to pursue long-term strategies, while giving the space credibility

Baby boomers poised to reshape clinical trials industry
Millions of tech-savvy consumers already track their health, expect new treatments as they age

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The CenterWatch Monthly

October

CROs driving changes in patient recruitment
Data- and tech-aided enrollment services a competitive advantage

Trials with in-home nurses poised to grow
Higher expense, but may improve recruitment and retention for select trials

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