R&D Trends

UT Southwestern to establish Center for Heavy Ion Radiation Therapy

Thursday, February 12, 2015 01:07 PM

UT Southwestern Medical Center is leading a Texas consortium of researchers to establish the country's first National Center for Heavy Ion Radiation Therapy that could provide clinical care and research using heavy particles for innovative new cancer treatments.

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Quest Diagnostics

Thiel Foundation's Breakout Labs selects three early-stage companies for funding

Thursday, February 12, 2015 01:05 PM

Breakout Labs, a seed-stage revolving fund operating out of the nonprofit Thiel Foundation in San Francisco, has announced three new companies have been selected for funding. These companies include Neumitra, Ion Dx, E3XBio.

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Advaxis, Incyte collaborate on early stage cervical cancer immunotherapies

Thursday, February 12, 2015 01:04 PM

Advaxis, a Princeton, N.J.-based clinical-stage biotechnology company developing cancer immunotherapies, has entered into a clinical trial collaboration agreement with Incyte to evaluate the combination of Advaxis's Lm-LLO cancer immunotherapy, ADXS-HPV (ADXS11-001), with Incyte's investigational oral indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, epacadostat (INCB24360). Incyte is a pharmaceutical company based in Alapocas, Del.

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Voyager Therapeutics, Genzyme collaborate on CNS disorders

Thursday, February 12, 2015 01:01 PM

Voyager Therapeutics, a gene therapy company headquartered in Cambridge, Mass. developing treatments for diseases of the central nervous system (CNS), and Genzyme, a Sanofi company and gene therapy pioneer, have announced a major strategic collaboration to discover, develop and commercialize novel gene therapies for severe CNS disorders. The collaboration will leverage Genzyme’s long-standing commitment and experience in adeno-associated virus (AAV) gene therapy and Voyager’s AAV product engine to develop breakthrough therapies for patients suffering from severe CNS disorders.

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Cellular Biomedicine Group, Chinese PLA General Hospital ink agreement

Wednesday, February 11, 2015 12:38 PM

Cellular Biomedicine Group, a Palo Alto, Calif.-based biomedicine company engaged in the development of cellular therapies for degenerative and cancerous diseases, has acquired Chinese PLA General Hospital's (PLAGH, Beijing, also known as 301 Hospital) Chimeric Antigen Receptor T cell (CAR-T) therapy; its recombinant expression vector CD19, CD20, CD30 and Human Epidermal Growth Factor Receptor's (EGFR or HER1) Immuno-Oncology patents (all pending); and phase I/II clinical data of the aforementioned therapies and manufacturing knowledge.

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International GPCR Consortium adds Novo Nordisk and Merck

Wednesday, February 11, 2015 12:34 PM

The GPCR Consortium, an international nonprofit collaboration that comprises academic research institutes in the U.S. and China and major pharma companies around the world, has announced Novo Nordisk and Merck as new members. The companies join AmgenSanofi and Ono in the GPCR Consortium. The research funded by the GPCR Consortium currently is conducted at the Bridge Institute at the University of Southern CaliforniaShanghai Institute of Materia Medica and the iHuman Institute at ShanghaiTech University.

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ALK, bioCSL partner for allergy tablets

Wednesday, February 11, 2015 12:30 PM

ALK and bioCSL have entered into a long-term partnership covering three ALK products in Australia and New Zealand. The agreement grants bioCSL exclusive rights in Australia and New Zealand to ALK’s sublingual allergy immunotherapy tablets (SLIT-tablets) for house dust mite (HDM) allergy and grass pollen allergy (marketed as Grazax in Europe and Grastek in North America), and its adrenaline auto-injector, Jext. ALK will be responsible for product supply and bioCSL will undertake registration and commercialization of the products.

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Adimab, Sanofi collaborate on bispecific antibodies

Monday, February 9, 2015 12:20 PM

Adimab, a Lebanon, N.H.-based technology company focused on the discovery of fully human antibodies and bispecifics, has announced a multi-target discovery and optimization collaboration with Sanofi. Adimab will use its proprietary platform to generate bispecific molecules against multiple targets. Sanofi will have the right to develop and commercialize all therapeutic antibodies and bispecifics resulting from the collaboration.

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Science for Life Laboratory forms Swedish National Center

Monday, February 9, 2015 12:09 PM

Science for Life Laboratory (SciLifeLab) has established the Swedish National Center for Single-Cell Biology. The center features six C1TM systems, three CyTOF 2 systems and a Biomark HD system, making SciLifeLab one of the preeminent users of the full line of Fluidigm’s single-cell technologies in the world. Fluidigm develops, manufactures and markets life science analytical and preparatory systems for growth markets such as single-cell biology and production genomics. Fluidigm products are provided for research use only.

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Exact Sciences, Mayo Clinic extend, expand collaboration

Monday, February 9, 2015 12:06 PM

Exact Sciences, a Madison, Wis.-based molecular diagnostics company, and Rochester, Minn.-based Mayo Clinic have announced a five-year extension and expansion of their collaboration, broadening their efforts to develop screening, surveillance and diagnostic tests beyond colorectal cancer to address other diseases within the gastrointestinal tract.

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Doctors, patients in the U.S. and U.K. agree: Mobile health apps are good for our health

AARP teams with Georgia Tech's HomeLab, Pfizer and UnitedHealthcare to test wearables with consumers 50+

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PSI, INC Research, Chiltern best with sites
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Regulatory compliance an increasing burden on sites
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Novo Nordisk, Takeda, Servier, Celgene among top sponsors
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Patient reported outcomes take center stage
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