Theorem Clinical Research

R&D Trends

Roche, BioMed X collaborate to develop nanomaterial-based biosensors

Thursday, February 26, 2015 03:30 PM

Roche and BioMed X, a collaboration model at the interface between academia and industry based in Heidelberg, Germany, have entered into a collaboration agreement to establish a research group focusing on the development of a novel sensor technology platform based on new nanomaterials such as graphene.

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Quest Diagnostics

Recursion Pharmaceuticals wins $1.5M NIH grant for rare diseases

Thursday, February 26, 2015 03:28 PM

Recursion Pharmaceuticals, an emerging biotech company founded in 2013 based on technology developed at the University of Utah, has been awarded $1.46 million from the NIH via the National Center for Accelerating Translational Sciences (NCATS). Just over half of the award is available in the first year; the rest will come through in year two pending availability of funds and project progress. The award will support the further development of Recursion’s Drug Screening Platform for hundreds of rare genetic diseases.

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Report: Global oncology drugs market is expected to reach $111.9B by 2020

Wednesday, February 25, 2015 11:31 AM

The global oncology market is forecasted to reach $111.9 billion by 2020, registering a CAGR of 7.1% from 2014 to 2020, according to a new report by Allied Market Research, titled Global Oncology/Cancer Drugs Market—Size, Industry Analysis, Trends, Opportunities, Growth and Forecast, 2013-2020.

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Orca Pharmaceuticals, AstraZeneca partner to treat autoimmune disease

Wednesday, February 25, 2015 11:23 AM

Orca Pharmaceuticals, a U.K. based biopharmaceutical company, and AstraZeneca have announced a three-year collaboration to develop inhibitors of retinoic acid–related orphan nuclear receptor gamma (RORγ). Inhibitors of this receptor are believed to have potential against a wide range of autoimmune diseases for which there currently is no safe, orally available and effective treatment.

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MedImmune, NIST partner to advance development of biological therapies

Monday, February 23, 2015 01:06 PM

MedImmune, the global biologics R&D arm of AstraZeneca, and the U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) have signed a five-year agreement to jointly support research that will help advance drug discovery and manufacturing. The effort will focus on tools and measurements that will be used in the development and production of biopharmaceuticals, which are drugs and treatments derived from biological, rather than chemical, sources.

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Rigel, Bristol-Myers Squibb ink R&D collaboration

Monday, February 23, 2015 01:01 PM

Rigel Pharmaceuticals and Bristol-Myers Squibb have entered into a collaboration agreement for the discovery, development and commercialization of cancer immunotherapies based on Rigel’s extensive portfolio of small molecule TGF beta receptor kinase inhibitors. T

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Merck Serono, Sysmex Inostics open liquid biopsy RAS biomarker testing center

Friday, February 20, 2015 12:32 PM

Merck Serono, the biopharmaceutical business of Merck, has announced the opening of the first liquid biopsy RAS biomarker testing center in Vall d'Hebron's Institute of Oncology, Barcelona, Spain, and initially will test patients as part of its research program. This is an important milestone in making the new liquid biopsy RAS test available to patients with metastatic colorectal cancer (mCRC), and a significant step forward in Merck Serono's collaboration with Sysmex Inostics, a Germany-based molecular diagnostic company.

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WHO urges governments to invest $34B for neglected tropical diseases

Friday, February 20, 2015 12:20 PM

The World Health Organization (WHO) has released a report urging countries to scale up their investment in tackling 17 neglected tropical diseases in order to improve the health and well-being of more than 1.5 billion people. This investment would represent as little as 0.1% of current domestic expenditure on health in affected low- and middle-income countries for the period 2015-2030.

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NIH expands tuberculosis research program, awards $105.3M

Thursday, February 19, 2015 02:40 PM

The National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, is expanding its Tuberculosis Research Units (TBRU) program in an effort to drive innovation in tuberculosis (TB) research. NIAID is awarding up to $15.2 million in fiscal year 2015 and as much as $105.3 million over seven years to fund four institutions that will act as a collaborative TBRU network.

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Heat Biologics, OncoSec Medical collaborate on immunotherapy platforms

Thursday, February 19, 2015 02:38 PM

Heat Biologics, a clinical stage biopharmaceutical company developing cancer immunotherapies based in Durham, N.C., and OncoSec Medical, a San Diego, Calif.-based company developing DNA-based intratumoral cancer immunotherapies, have entered into an agreement to evaluate the combination of the immunotherapy approaches developed by each company.

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March 2

Huntingdon Life Sciences-Harlan prepares for rebranding and U.S. expansion to compete with early phase CROs Covance, CRL

Patients' increased sharing of clinical trial experiences through social media can help sponsors improve outcomes, enrollment

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The CenterWatch Monthly

March

Novo Nordisk, Takeda, Servier, Celgene among top sponsors
New gains seen from patient- and site-centric initiatives

Patient reported outcomes take center stage
FDA combining PROs, clinical outcomes in its approval decisions

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February

Study grants market breaks $13 billion
Volume of clinical activity rising while growth in grant spending slows

Revisiting eClinical Technology Solutions Adoption
While use of established solutions grows, sponsors hesitate on newer tools

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