R&D Trends

U.K. announces $21M investment in stratified medicine

Friday, January 30, 2015 12:29 PM

Minister for Life Sciences George Freeman has announced a further $20.6 million investment in stratified medicine collaborations funded by the Medical Research Council (MRC). Four new awards bring the total of stratified medicine consortia funded by the MRC to 13, with investments totaling over $21 million—part of the government’s $195.4 million commitment to stratified medicine set out in the U.K. life sciences strategy.

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Astellas Pharma, Immunomic Therapeutics collaborate

Friday, January 30, 2015 12:25 PM

Immunomic Therapeutics, a company developing next-generation vaccines based on the LAMP-vax platform headquartered in Hershey, Pa., and Astellas Pharma of Tokyo have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen. The companies expect to initiate a phase I trial of JRC2-LAMP-vax in Japan as soon as it is ready.

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Sigma-Aldrich, VIB ink alliance on novel translational research tools

Friday, January 23, 2015 11:46 AM

Sigma-Aldrich's research business unit, which supports translational researchers by supplying the products, services and solutions needed to enable scientific discovery, has formed an alliance with VIB, a life science research institute based in Flanders, Belgium, focused on translational research in medical, agricultural and industrial applications. The alliance will focus on the commercialization and supply of new tools and technologies to help meet the evolving needs of translational researchers.

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Array to acquire Novartis BRAF inhibitor encorafenib (LGX818)

Friday, January 23, 2015 11:40 AM

Array BioPharma, based in Boulder, Colo., has reached a definitive agreement with Novartis Pharma to acquire worldwide rights to encorafenib (LGX818), a BRAF inhibitor currently in phase III development. This agreement is conditional on the closing of transactions announced by Novartis and GlaxoSmithKline on April 22, 2014, which are expected to close in the first half of 2015, and the agreement remains subject to the receipt of regulatory approvals.

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Curis, Aurigene collaborate for immuno-oncology and precision oncology targets

Thursday, January 22, 2015 12:14 PM

Curis, a Lexington, Mass.-based biotechnology company focused on the development and commercialization of innovative drug candidates for the treatment of human cancers, and Aurigene Discovery Technologies, a Bangalore, India-based, specialized, discovery stage biotechnology company developing novel therapies to treat cancer and inflammatory diseases, have entered into an exclusive collaboration agreement focused on immuno-oncology and selected precision oncology targets.

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Zymeworks, Celgene collaborate

Thursday, January 22, 2015 12:12 PM

Zymeworks, a privately held biotherapeutics company based in Vancouver, has formed a collaboration and licensing agreement with Celgene for the research, development and commercialization of bi-specific antibody therapeutics enabled using Zymeworks’ proprietary Azymetric platform.

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Report: Midwest healthcare companies raise $1.8B in 2014

Wednesday, January 21, 2015 01:06 PM

Midwest healthcare companies attracted $1.8 billion in new investments across 243 companies in 2014, according to the BioEnterprise Midwest Healthcare Growth Capital Report. The totals are the highest recorded in both dollars and number of companies funded since BioEnterprise began compiling the report in 2005, surpassing the banner 2007 by 46% and 2013 by 135%. BioEnterprise is a business formation, recruitment, and acceleration initiative designed to grow healthcare companies and commercialize bioscience technologies based in Cleveland, Ohio.

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BioInvent inks agreement with Cancer Research U.K., CRT and LLR

Wednesday, January 21, 2015 01:02 PM

BioInvent International, a research-based pharmaceutical company based in Sweden, has reached an agreement with Cancer Research U.K.Cancer Research Technology (CRT), the charity’s development and commercialization arm, and Leukemia & Lymphoma Research (LLR) to take its investigational drug, BI-1206, into a collaborative phase I/II trial for patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).

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Trovagene, Genomac expand collaboration

Wednesday, January 21, 2015 12:57 PM

Trovagene, a provider of technology for the detection and monitoring of cell-free DNA headquartered in San Diego, will expand its clinical collaboration with Genomac Research Institute in Prague, Czech Republic. Trovagene Precision Cancer Monitoring technology will be used in two prospective clinical studies for the early detection of emerging oncogene mutations indicative of resistance to targeted therapies used to treat colorectal and lung cancer.

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Johnson & Johnson forms Ebola vaccine development consortia

Monday, January 19, 2015 12:48 PM

Johnson & Johnson has formed a consortia with leading global research institutions and non-government organizations to work in conjunction with Janssen Pharmaceutical to accelerate the development of its Ebola vaccine regimen. The Innovative Medicines Initiative (IMI) plans to award these consortia grants totaling more than $116 million from the Ebola+ program to support the development, manufacturing and patient education for the vaccine regimen.

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CenterWatch
CWWeekly

January 26

2015 CRO outlook: M&As, IPOs, strategic partnerships and increased eClinical outsourcing expected to continue

IOM, industry stakeholders propose standards, guidelines for open sharing of clinical trial data

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The CenterWatch Monthly

January

All eyes on EMA’s adaptive licensing pilot
Sponsors could offer innovative drugs to patients 8 years sooner

Ice Bucket Challenge a boon for ALS research
Donations soar, but phenomenon difficult to replicate

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The CenterWatch Monthly

December

Growing adoption of feasibility review committees
Early reports cite fewer amendments, improved cycle time

AMCs vying to better compete for industry trials
Working to conquer study start-up delays, IRB review process

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