Drug Sponsors

The Medicines Company acquires Annovation Biopharma

Thursday, February 5, 2015 12:08 PM

The Medicines Company has completed its acquisition of all of the outstanding equity of Annovation Biopharma, a company focused on creating more effective, safer therapies for anesthesia and critical care. Based on technology licensed from Massachusetts General Hospital, Annovation is developing ABP-700, a novel intravenous anesthetic which in phase I clinical studies has demonstrated potent and rapidly reversible anesthetic effects.

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Quest Diagnostics

Pfizer to acquire Hospira for $17 billion

Thursday, February 5, 2015 12:06 PM

Pfizer has agreed to acquire Hospira, a provider of injectable drugs and infusion technologies and a global provider in biosimilars headquartered in Lake Forest, Ill., for $90 a share in cash, for a total enterprise value of approximately $17 billion.

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Water Street invests in generic injectable drug services company Custopharm

Wednesday, February 4, 2015 01:32 PM

Water Street Healthcare Partners, a strategic investor focused exclusively on the healthcare industry headquartered in Chicago, has invested in Custopharm, a generic injectable drug services company. Water Street's team has committed equity to both acquire and expand the Carlsbad, Calif.-based company. The healthcare firm has recruited William Larkins, Ph.D., former vice president and general manager of Bedford Laboratories, as CEO of Custopharm.

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Viropro plans for restructuring following facility seizure

Wednesday, February 4, 2015 01:23 PM

Viropro, an integrated developer and manufacturer of biopharmaceutical products based in San Jose, Calif., has announced that its board of directors completed its strategic review and has begun the implementation of a restructuring designed to restore the company to financial health. 

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OptiKira launched by BioMotiv, UCSF, University of Washington

Wednesday, February 4, 2015 01:18 PM

BioMotiv, a drug development accelerator associated with The Harrington Project, the University of California San Francisco (UCSF) and University of Washington, Seattle, have announced the formation of OptiKira, a platform company that will develop small molecule therapeutics that prevent cell death in pathologies caused by misfolded or unfolded proteins.

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Astellas broadens commitment to clinical trial data transparency

Monday, February 2, 2015 01:57 PM

Astellas Pharma, based in Japan, will now make trial data available through www.clinicalstudydatarequest.com, an independent web site that enables researchers to request and access clinical trial data after approval of a research proposal by an independent review panel.

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Biogen Idec begins 2015 with multiple collaborations

Monday, February 2, 2015 01:45 PM

Biogen Idec left 2014 with cash, cash equivalents and marketable securities totaling approximately $3.3 billion and has begun 2015 with multiple collaborations. The company expects to continue to bolster its R&D capabilities in the coming months.

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Valeant to acquire assets from bankrupt Dendreon

Monday, February 2, 2015 01:41 PM

Valeant Pharmaceuticals International, based in Canada, has entered into a "stalking horse" asset purchase agreement to acquire certain assets of Seattle, Wash.-based biotechnology company Dendreon for $296 million in cash.

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Endo Pharmaceuticals completes acquisition of Auxilium Pharmaceuticals

Monday, February 2, 2015 01:38 PM

Endo International has completed the acquisition of Auxilium Pharmaceuticals in a transaction valued at $2.6 billion. The closing of the transaction, which was announced Oct. 9, 2014, follows approval by Auxilium's shareholders on Jan. 27 and the receipt of all required regulatory approvals.

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AstraZeneca collaborates to use CRISPR technology

Friday, January 30, 2015 12:27 PM

AstraZeneca has announced four research collaborations aimed at harnessing the power of CRISPR, a pioneering genome-editing technique, across its entire discovery platform in the company’s key therapeutic areas. The four research collaborations are with the Wellcome Trust Sanger Institute, Cambridge, U.K.; the Innovative Genomics Initiative, California; Thermo Fisher Scientific, Waltham, Mass.; and the Broad Institute/Whitehead Institute, Cambridge, Mass. The technology will allow AZ to identify and validate new drug targets in preclinical models that closely resemble human disease.

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CWWeekly

April 13

Quintiles-Quest Diagnostics joint venture latest in CRO-central lab deals, more could be on horizon

Biotech companies raise record amount of capital in Q1

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The CenterWatch Monthly

April

PSI, INC Research, Chiltern best with sites
Strategic outsourcing prioritizing, improving site relationships

Regulatory compliance an increasing burden on sites
Increased staff time, materials, storage eroding site operating profit

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March

Novo Nordisk, Takeda, Servier, Celgene among top sponsors
New gains seen from patient- and site-centric initiatives

Patient reported outcomes take center stage
FDA combining PROs, clinical outcomes in its approval decisions

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