National MS Society, GE Healthcare partner

Wednesday, October 2, 2013 01:08 PM

The National Multiple Sclerosis Society is collaborating with GE Healthcare through Fast Forward, a nonprofit subsidiary of the National Multiple Sclerosis Society, to co-fund a clinical study with the GE investigational PET tracer, GE180, in patients with multiple sclerosis (MS). The clinical study, which will be enrolling patients in the U.K., is aimed to aid in physicians' understanding of whether imaging neuroinflammation in MS patients before and after treatment with natalizumab (Tysabri) can help identify which patients may respond to treatment.

In MS, the immune system damages and destroys myelin, the material that surrounds and protects nerve fibers, in the brain and spinal cord. Research is showing that microglia, a type of immune cell in the brain and spinal cord, becomes active early in MS and participates in MS attacks. GE180 binds to a molecule on the surface of microglia known to be more active following inflammation. A PET scan with GE180 may prove ideal for studying responses to disease-modifying therapies in MS.  In addition, this technology may have application in detecting inflammation in progressive forms of MS.

Share:          
CLINICAL TRIAL RESOURCES

Search:

NEWS ONLINE ARCHIVE

Browse by:

CWWeekly

September 30

Novartis-Walgreens pilot study blurring the line between retail pharmacy, investigative site

CISCRP to launch traveling science museum exhibit to demystify clinical trial participation

Already a subscriber?
Log in to your digital subscription.

Subscribe to CWWeekly.

The CenterWatch Monthly

October

New growth and decline in Asia clinical trials
South Korea, Japan, China see big growth in 1572s, while India posts huge drop

Harnessing Big Data to transform clinical trials
From protocol to patient recruiting, data analytics can yield valuable insights

Already a subscriber?
Log in to your digital subscription.

Purchase the October issue.

Subscribe to
The CenterWatch Monthly.

The CenterWatch Monthly

September

Sponsors look to collaborate on comparator drugs
Co-therapies, comparators are in 60% of studies, cost $25m per company a year

Early adopters implement risk-based monitoring pilot programs
Experiments aim to offer long-term solutions, despite short-term uncertainties

Already a subscriber?
Log in to your digital subscription.

Purchase the September issue.

Subscribe to
The CenterWatch Monthly.

JobWatch centerwatch.com/jobwatch

Featured Jobs