R-Pharm licenses Merck hepatitis C drug

Friday, July 6, 2012 03:59 PM

The Russian pharmaceutical company R-Pharm—headed by the Ministry of Industry and Trade of the Russian Federation—entered into a licensing agreement with MSD (Merck) for rights to a novel investigational, hepatitis C once-daily protease inhibitor, narlaprevir. 

The agreement provides an opportunity for R-Pharm to conduct late-stage clinical trials in Russia, which is among the goals of the Russian government's Pharma 2020 initiative. R-Pharm will gain rights to develop and commercialize narlaprevir in Russia and the Commonwealth of Independent States (CIS). R-Pharm will pay MSD (acting through a subsidiary), an upfront payment and undisclosed royalties on sales of narlaprevir. Merck has retained the right to co-promote narlaprevir in these regions and retains rights to the drug outside of Russia and the CIS countries.

Narlaprevir is a second generation NS3 serine protease inhibitor developed by MSD.  In a phase IIa clinical study, narlaprevir administration resulted in a robust decline in the level of hepatitis C virus detected in the blood and high sustained viral response rates when followed by standard of care in both treatment-experienced and treatment-naïve HCV genotype 1-infected patients.

"MSD is pleased that through this agreement, R-Pharm can pursue the development of this potentially important technology for the treatment of hepatitis C, an area of substantial unmet need in Russia," said Kevin Ali, president of emerging markets, MSD. "This unique technology transfer deal is consistent with the Russian government's desire to create a stronger local innovative pharma industry to drive economic growth in the sector. Developing narlaprevir will enable R-Pharm to gain deep experience in late stage clinical trials—the crucial phase of drug development."

Share:          
CLINICAL TRIAL RESOURCES

Search:

NEWS ONLINE ARCHIVE

Browse by:

CWWeekly

October 20

Toronto Star, with FDA data, exposes weaknesses in Health Canada's clinical trial, inspection oversight

Crowdsourcing effort aims to fund updated online social media guide for sponsor interaction with patients

Already a subscriber?
Log in to your digital subscription.

Subscribe to CWWeekly.

The CenterWatch Monthly

September

Today's fastest, most economical sponsors
Standout sponsors reveal how they shorten regulatory, clinical cycle times

From the trenches: Sites' eye view of state of the industry
CW’s first site focus groups uncover frustration with 'progress,' but a passion for their mission

Already a subscriber?
Log in to your digital subscription.

Purchase the September issue.

Subscribe to
The CenterWatch Monthly.

The CenterWatch Monthly

August

Reality of costs and impact rain on Sunshine Act
Concerns mount over compliance burden on CROs, sponsors, unanticipated consequences for research

Cloud computing expanding into all areas of clinical trial conduct
Benefits outweigh the complexities, challenges of finding right vendors

Already a subscriber?
Log in to your digital subscription.

Purchase the August issue.

Subscribe to
The CenterWatch Monthly.

JobWatch centerwatch.com/jobwatch

Featured Jobs