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Adopting predictive analytics

Monday, April 6, 2015 08:00 AM

The 2008 financial crisis had a crippling effect on businesses operating within the financial sector.

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Quest Diagnostics

Daiichi Sankyo, Asubio Pharmaceuticals to merge

Friday, April 3, 2015 01:41 PM

Daiichi Sankyo, Inc., the U.S. subsidiary of Daiichi Sankyo Company, will merge with its U.S.-based sister company, Asubio Pharmaceuticals. As a result, Asubio Pharmaceuticals projects will be integrated into the Daiichi Sankyo global development organization, led by Mahmoud Ghazzi, M.D., Ph.D.

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Sanofi, Schrödinger ink $120M drug design pact

Friday, April 3, 2015 01:39 PM

Schrödinger, a global provider of advanced molecular simulations and enterprise software solutions and services for life sciences and materials research, has entered into a collaboration with Sanofi in which Schrödinger will provide comprehensive computational drug design support, from target analysis and validation to lead identification and lead optimization, for as many as ten drug discovery programs. Schrödinger could receive up to $120 million under the terms of the broad, multi-year relationship that includes preclinical milestones.

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Oramed enrolls first patient in glucose clamp study for oral insulin

Friday, April 3, 2015 10:22 AM

Oramed Pharmaceuticals, a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, has enrolled the first patient in its glucose clamp study. The study will be performed at the University of Texas Health Science Center at San Antonio and University Health System's Texas Diabetes Institute under the supervision of Professor Ralph DeFronzo.

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PPD appoints Jon Denissen VP GMP laboratory services

Friday, April 3, 2015 10:18 AM

Pharmaceutical Product Development (PPD) has appointed Jon Denissen, Ph.D., as vice president of good manufacturing practices (GMP) laboratories. Denissen brings over 25 years of experience in the pharmaceutical and CRO industries. He is based in PPD’s GMP lab facility in Middleton, Wis.

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Douglas Lowy named acting director of the National Cancer Institute

Friday, April 3, 2015 10:12 AM

Douglas Lowy, M.D., has been named the National Cancer Institute’s acting director. NCI is one of the 27 institutes and centers that comprise the NIH. Lowy has worked as NCI’s deputy director since July 2010, helping lead NCI’s key scientific initiatives since that time.

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Clinical trials prove Canada's VSV-EBOV Ebola vaccine safe and effective

Thursday, April 2, 2015 02:46 PM

Canada's VSV-EBOV Ebola vaccine proved to be safe and effective in a phase I clinical trial, according to findings published in the New England Journal of Medicine. These studies were performed at the Walter Reed Army Institute of Research and the National Institute of Allergy and Infectious Diseases to explore the experimental vaccine's safety and what immune response it evokes when administered at different dosages.

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Enzalutamide, bicalutamide demonstrate positive results in Strive trial

Thursday, April 2, 2015 01:38 PM

Astellas Pharma and Medivation has announced topline results from the phase II STRIVE trial comparing enzalutamide with bicalutamide in a study population of men with non-metastatic or metastatic castration-resistant prostate cancer. The study achieved its primary endpoint demonstrating a statistically significant increase in progression-free survival (PFS) for enzalutamide compared with bicalutamide (Hazard Ratio = 0.24; 95% Confidence Interval, 0.18-0.32; p<0.0001). Median PFS was 19.4 months in the enzalutamide group compared with 5.7 months in the bicalutamide group.

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TPG completes acquisition of Aptalis, renames company Adare Pharmaceuticals

Thursday, April 2, 2015 01:08 PM

Aptalis Pharmaceutical Technologies has announced that its divestiture from Actavis to TPG, a Texas-based global private investment firm, has been completed. The company also announced its new name is Adare Pharmaceuticals, and John Fraher, who was president of Aptalis Pharmaceutical Technologies, has been named CEO. He is joined by key executives from his current management team.

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Certara launches Cardiac Safety Simulator V2.0

Thursday, April 2, 2015 01:07 PM

Certara, a Princeton, N.J.-based global biosimulation technology-enabled consultancy, has launched version 2.0 of its Cardiac Safety Simulator (CSS), which has become a standalone product for the first time.

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April 20

Christie Clinic, PMG Research's 12th clinical research site, expands its geographic reach north to Illinois

Clinipace acquires Accovion to expand European presence, following an infusion of equity that could lead to more deals

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The CenterWatch Monthly


PSI, INC Research, Chiltern best with sites
Strategic outsourcing prioritizing, improving site relationships

Regulatory compliance an increasing burden on sites
Increased staff time, materials, storage eroding site operating profit

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Novo Nordisk, Takeda, Servier, Celgene among top sponsors
New gains seen from patient- and site-centric initiatives

Patient reported outcomes take center stage
FDA combining PROs, clinical outcomes in its approval decisions

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