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Broad Institute, Bayer Healthcare expand partnership

Wednesday, April 1, 2015 01:01 PM

The Broad Institute of MIT and Harvard has expanded its collaboration with Bayer HealthCare to include cardiovascular genomics and drug discovery. The goal of this new part of the alliance is to leverage insights from human genetics to help create new cardiovascular therapies.

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Quest Diagnostics

Fujifilm to acquire Cellular Dynamics International

Wednesday, April 1, 2015 01:00 PM

Fujifilm, a multinational photography and imaging company headquartered in Tokyo, has entered into a definitive agreement to acquire Cellular Dynamics International (CDI), a developer and manufacturer of fully functioning human cells in industrial quantities to precise specifications, via an all-cash tender offer to be followed by a second step merger.

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BARDA awards $35M contract to BioCryst’s BCX4430

Wednesday, April 1, 2015 12:58 PM

The Biomedical Advanced Research and Development Authority (BARDA) within the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response (ASPR) has awarded Durham, N.C.-headquartered BioCryst Pharmaceuticals a contract for the continued development of BCX4430 as a potential treatment for diseases caused by RNA pathogens, including filoviruses.

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Quintiles, Quest Diagnostics to form joint venture to provide global trial lab services

Wednesday, April 1, 2015 12:57 PM

Quintiles and Quest Diagnostics, a Madison, N.J.-based provider of diagnostic information services, have agreed to form a global clinical trials laboratory services business. The new entity will provide customers with a depth of capabilities and end-to-end clinical trial lab services.

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Syndax, Merck to collaborate on immuno-oncology study

Wednesday, April 1, 2015 12:54 PM

Syndax Pharmaceuticals, based in Waltham, Mass., and Merck have entered into a clinical trial collaboration to evaluate the safety and efficacy of combining Syndax’s entinostat, an investigational epigenetic therapy, with Merck’s Keytruda (pembrolizumab), the first anti-PD-1 therapy approved in the U.S. The phase Ib/II study will evaluate this novel combination regimen in patients with either advanced non-small cell lung cancer (NSCLC) or melanoma. The study is expected to begin enrolling patients in the second half of 2015.

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Ziopharm-Intrexon collaborate with Merck Serono

Wednesday, April 1, 2015 12:50 PM

Ziopharm Oncology, a Boston, Mass.-based biotech company, and Intrexon, a synthetic biology provider, have announced their oncology programs will be strengthened through Intrexon's new global collaboration focused exclusively on novel chimeric antigen receptor T-cell (CAR-T) products with Merck Serono, the biopharmaceutical division of Merck. Intrexon will share the economic provisions of this collaboration, including upfront payment, milestones and royalties, equally with Ziopharm.

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Aduro Biotech, Novartis collaborate on immuno-oncology products

Wednesday, April 1, 2015 12:50 PM

Aduro Biotech, a private, clinical-stage immuno-oncology company based in Berkeley, Calif., is collaborating with Novartis for the worldwide research, development and commercialization of novel immuno-oncology products derived from Aduro’s cyclic dinucleotide (CDN) approach to target the STING (Stimulator of Interferon Genes) receptor, that, when activated, is known to initiate broad innate and adaptive tumor-specific immune responses.

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INC Research, SCRS award more than 100 clinical research scholarships

Wednesday, April 1, 2015 12:42 PM

INC Research, a Raleigh, N.C.-based global CRO, together with the Society for Clinical Research Sites (SCRS), an Ellicott City, Md.-based global trade organization representing clinical research sites, have collectively awarded scholarship-based memberships to more than 100 sites worldwide through the SCRS Site Scholarship Program.

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The CenterWatch Monthly, April 2015

Wednesday, April 1, 2015 08:42 AM

PSI, INC Research, Chiltern best with sites

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Survey: PSI, INC Research, Chiltern rated top CROs by investigative sites

Wednesday, April 1, 2015 08:00 AM

More than 1,900 global investigative sites rate the best CROs for which to work in a new survey conducted by CenterWatch, a provider of global clinical trials information. The survey results were released in the April issue of The CenterWatch Monthly newsletter.

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CWWeekly

April 27

Doctors, patients in the U.S. and U.K. agree: Mobile health apps are good for our health

AARP teams with Georgia Tech's HomeLab, Pfizer and UnitedHealthcare to test wearables with consumers 50+

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The CenterWatch Monthly

April

PSI, INC Research, Chiltern best with sites
Strategic outsourcing prioritizing, improving site relationships

Regulatory compliance an increasing burden on sites
Increased staff time, materials, storage eroding site operating profit

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The CenterWatch Monthly.

The CenterWatch Monthly

March

Novo Nordisk, Takeda, Servier, Celgene among top sponsors
New gains seen from patient- and site-centric initiatives

Patient reported outcomes take center stage
FDA combining PROs, clinical outcomes in its approval decisions

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