Effexor (venlafaxin HCL)
The following drug information is obtained from various newswires, published
medical journal articles, and medical conference presentations.
General Information
Effexor was approved for the treatment of depression in 1993.
Effexor increases the levels of both serotonin and norepinephrine
(two neurotransmitters though to cause the symptoms of depression)
in the brain.
Effexor's latest approval is for the treatment of anxiety
disorder. It is estimated that 95% of people with depression
experience at least one symptom of anxiety, including excessive or
uncontrollable worry, apprehension, irritability, and muscle
tension. Studies suggest that co-morbid depression and anxiety may
have an impact on a patient's social functioning and is
associated with a 30% to 60% increase in the utilization of
healthcare services.
Side Effects
Some of the side effects of Effexor include the following:
- headache
- nausea
- weight loss
- constipation
- blurry vision
- diarrhea
- dizziness
- dry mouth
- increased blood pressure
Mechanism of Action
Effexor affects various neuro chemicals in the body which are
responsible for nervous system regulation. It inhibits specifically
norepinephrine and serotonin reuptake, and also weakly inhibits
dopamine reuptake. The net result is more neuro chemicals
circulating in the nervous system.
Additional Information
Pregnancy and Breastfeeding Issues
If you are pregnant, plan to become pregnant, or breastfeeding,
discuss the potential risks of this or any medication with your
doctor.
It is also recommended that you talk to your doctor about
Effexor if you have: high blood pressure, heart, liver, or kidney
disease.
