The following drug information is obtained from various newswires, published
medical journal articles, and medical conference presentations.
Marplan is indicated for the treatment of depression. Because of
its potentially serious side effects, it is not recommended as an
anti-depressant of first choice in the treatment of newly diagnosed
The effectiveness of Marplan for long-term use, meaning longer
than 6 weeks, has not been fully evaluated by trials.
Marplan can cause serious side effects. It is not recommended as
initial therapy but should be reserved for patients who have not
responded satisfactorily to other anti-depressants.
Some side effects include: headaches, palpitation, neck
stiffness, nausea or vomiting, sweating (fevers or clammy skin),
photophobia, tachycardia, bradycardia, constricting chest pain,
dilated pupils, intracranial bleeding and increased blood