Skip Navigation



Home » Drug Information » FDA Approved Drugs » 1997
Medical Areas: Endocrinology | Nephrology

View By:YearCompanyConditionsTherapeutic AreasDrug Names


The following drug information is obtained from various newswires, published medical journal articles, and medical conference presentations.

Company: Roche
Approval Status: Approved December 1997
Treatment Area: rejection of kidney transplants

General Information

Hoffman-La Roche's new monoclonal antibody drug, Zenapax (daclizumab), has been approved to prevent rejection of kidney transplants. The drug uses the body's own immune system to prevent the acute rejection that can make kidney transplants fail.

Clinical Results

The FDA said its approval was based on two clinical trials that showed Zenapax significantly reduced acute rejections in patients who got the drug along with the standard three-drug cocktail of immunosuppressant drugs. Patients on Zenapax had 37 to 40% fewer rejections episodes than those given an inert placebo.