Home » Drug Information » FDA Approved Drugs » 1996
Medical Areas: Pulmonary/Respiratory Diseases | Infections and Infectious Diseases
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Nasacort AQ (triamcinolone acetonide) Nasal Spray
The following drug information is obtained from various newswires, published
medical journal articles, and medical conference presentations.
Company: Rhone Poulenc Rorer
Approval Status: Approved May 1996
Treatment Area: allergic rhinitis
Nasacort AQ Nasal Spray has been approved for the treatment of
seasonal and perennial allergic rhinitis symptoms indicated for
adults and children over the age of 12.
Contained in an aqueous microcrystalline suspension that does
not use chloroflurocarbon (CFC) propellants, Nasacort AQ represents
a new formulation of the active ingredient, triamcinolone
acetonide. RPR will also continue to market its once-daily aerosol
formulation of triamcinolone acetonide.
Each metered pump spray bottle of Nasacort AQ provides at least
120 actuations. It is recommended that once-daily dosing begin at
220 micrograms (two sprays in each nostril) for adults and children
12 years and older.
The safety and efficacy of Nasacort AQ has been demonstrated in
ten placebo-controlled, double-blind studies involving more than
1,200 subjects ages 12 years and older with seasonal or perennial
allergic rhinitis. These studies showed that compared to placebo,
once-daily Nasacort AQ provides statistically significant relief of
nasal symptoms including sneezing, stuffiness, discharge, and
Nasacort AQ is generally well tolerated. The most commonly
reported side effects observed in clinical trials included sore
throat, nosebleed, and cough.
An estimated 40 million Americans suffer from seasonal and
perennial allergic rhinitis, which produce symptoms including nasal
itch, congestion, runny nose, sneezing, and watery eyes.
Seasonal allergic rhinitis--commonly known as hay fever--is
caused by allergens present at specific times of the year, such as
tree pollens in the spring. Perennial allergic rhinitis is caused
by allergens in the environment all year, such as dust mites, mold,
mildew, or pet dander.