Home » Drug Information » FDA Approved Drugs » 1998
Medical Areas: Oncology
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The following drug information is obtained from various newswires, published
medical journal articles, and medical conference presentations.
Approval Status: Approved April 1998
Treatment Area: postoperative vomiting and nausea in adults
An intramuscular administration of Zofran for postoperative
nausea and vomiting in adults has been approved by the FDA.
Normally, Zofran is given through an IV injection or in tablet
form. This new intramuscular (IM) administration bypasses
difficulties some patients may encounter. For example, some
patients have difficulty swallowing, have small veins, or have
veins that won't allow an IV to enter.
While IM administration has been approved in adults, it has not
gained clearance for use in children.
Negative side effects have been noted in postoperative clinical
tests The most common are dizziness, headache, drowsiness,
sedation, and constipation. Other adverse effects are diarrhea, dry
mouth, and skin rash.