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Home » Drug Information » FDA-Approved Drugs » 1996
Medical Areas: Ophthalmology

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Drug Information

The following information is obtained from various newswires, published medical journal articles, and medical conference presentations.

Drug Name: Alphagan (brimonidine)

Company: Allergan
Approval Status: Approved September 1996
Treatment Area: open-angle glaucoma and ocular hypertension

General Information

Alphagan has been approved for the treatment of open-angle glaucoma and ocular hypertension.

Mechanism of Action

Alphagan is a selective alpha-2 agonist, which significantly lowers intraocular pressure with minimal effects on cardiovascular and pulmonary parameters. Its unique dual mechanism of action lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow.

Additional Information

Glaucoma, an eye disease commonly characterized by excessive intraocular pressure, is a leading cause of blindness in the world.


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