Home » Drug Information » Recently Approved Drugs » 1996
Medical Areas: Endocrinology | Rheumatology
Drug Information
The following information is obtained from various newswires, published
medical journal articles, and medical conference presentations.
Company: Wyeth-Ayerst Laboratories
Approval Status: Approved July 1996
Treatment Area: rheumatoid arthritis
Lodine has been approved for the treatment of rheumatoid
arthritis. Lodine is a nonsteroidal anti-inflammatory drug
(NSAID).
At the same time the FDA has cleared for market a new 500 mg
dosage strength.
The safety and efficacy of Lodine in relieving the signs and
symptoms of rheumatoid arthritis were established in a three-year,
double-blind, multicenter clinical trial involving 1,446 subjects
with active rheumatoid arthritis. Data from the study indicated
that doses of Lodine at 1,000 mg/day were efficacious and well
tolerated in subjects being treated for active rheumatoid
arthritis.
Lanza F, Rack MF, Lynn M et al. "An endoscopic comparison
of the effects of etodolac, indomethacin, ibuprofen, naproxen, and
placebo on the gastrointestinal mucosa." J
Rheumatology 1987; 14:338-341.
