Clinical Trials Resource Center

New Medical Therapies™


Patient Medical Areas

June 9, 2003

Point therapeutics reported positive results from a phase I trial investigating PT-100, a cytokine and chemokine stimulator for the treatment of chemotherapy-induced neutropenia. Results showed a two-day reduction in the median days of severe neutropenia observed in a group of seven subjects who received the 800mcg dose from the second to the eighth day following chemotherapy. A comparison of the median absolute neutrophil counts demonstrated approximately a 60 % reduction in the duration and degree of severe neutropenia in Cycle 2 compared with Cycle 1. The study compared the duration of severe neutropenia in cycle 1 of chemotherapy, when subjects did not receive PT-100, with the duration in cycle 2, when PT-100 was administered. The trial was designed to study the safety of PT-100 in cancer patients receiving chemotherapy and to measure blood levels of neutrophils and important biological mediators of hematopoiesis, such as G-CSF and IL-6.

This information does not represent a Lupus Research Institute endorsement of any listed study. It is merely a notice that the study is available. If you are presently under the care of a physician for lupus or other conditions, you should not disrupt your current program without discussing it with your doctor(s). Do not contact the Lupus Research Institute for information on these studies. Only contact the listed numbers. The Lupus Research Institute does not have any jurisdiction over or further involvement with these studies, other than to make people aware that they are being conducted.