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Therapeutic Areas: Neurology | Psychiatry/Psychology
Disease Category: Attention Deficit/Hyperactivity Disorder (ADHD - Adults)

Trial Information

Positron Emission Tomography (PET)Studies in Attention Deficit Disorder: Role of Dopamine

The purpose of this study is to determine if adults with Attention Deficit/Hyperactivity Disorder (ADHD) have changes in the brain chemical called dopamine. Participants with and without Attention Deficit/Hyperactivity Disorder will be compared in this research project. Three brain scans known as positron emission tomographies (PET) will be used to examine the differences in dopamine levels and dopamine genes in ADHD and non-ADHD participants. The PET scan will involve injections of substances used to increase the production of dopamine in the brain. This project also includes blood draws and questionnaires. Treatment for ADHD in not included as part of this project. These research- related procedures are provided at no cost. Participants will also be reimbursed for their time.
Compensation Provided

Patient Inclusion/Exclusion Criteria:

Participants with and without ADHD:
Ages 18-45

Participants with ADHD:
Meet criteria for ADHD


For participants with and without ADHD:
No present or past history of drug abuse
No other presence of psychiatric disorders
No medical conditions that may alter brain function
No heart disease or high blood pressure
Cannot participate if pregnant or breastfeeding.
No exposure to stimulant medication (like Ritalin, Adderall, Dexedrine) within past 6 months.

Participants with ADHD:
No previous treatments for ADHD except for short treatment periods of less than 2 months at least 6 months prior to starting the study.

Robyn C Palmero, M.A.,CCRC
Mount Sinai Medical Center
One Gustave L. Levy Place

New York, NY 10029
Phone: 212-659-8833
Fax: 212-849-2690
EMail: robyn.palmero@mssm.edu

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