Clinical Trial Details


Research Study Summary

A 15-week, Phase 2, Double Blind, Randomized, Placebo-controlled, Flexible Dose Study To Investigate The Efficacy, Safety And Tolerability Of Pf-06649751 In Subjects With Early Stage Parkinson's Disease

The purpose of this study is to evaluate the efficacy, safety and tolerability of PF-06649751 in Parkinson's disease patients at early stage of the disease.
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CW ID: 222922
Date Last Changed: February 3, 2017

Clinical Trial Snapshot

Both Male and Female
45 to 80 Years
Overall Status
Lead Sponsor
Facility Type


Inclusion Criteria:
  • Females of non-childbearing potential and/or male subjects
  • Clinical diagnosis of Parkinson's disease.
  • Parkinson's Disease Hoehn & Yahr Stage I-III inclusive
  • Treatment naïve or history of prior incidental treatment with dopaminergic agents for no more than 28 days
  • Able to refrain from any Parkinson's disease medication not permitted by the protocol.

    Exclusion Criteria:

  • History or presence of atypical Parkinsonian syndrome.
  • Severe acute or chronic medical or psychiatric condition or cognitive impairment or laboratory abnormality.
  • Any condition possibly affecting drug absorption.
  • Participation in other studies involving investigational drug(s), or treatment with any investigational drug within 30 days.
  • Contact

    Leigh Donharl
    University of South Florida - USF Health Byrd Alzheimer's Institute
    4001 Fletcher Ave
    Tampa, FL 33613
    Phone: (813) 396-0763

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