Clinical Trial Details


Research Study Summary

A Second Phase 3 Randomized, 12-Week, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Plecanatide in Patients with Irritable Bowel Syndrome with Constipation (IBS-C)


The purpose of the study is to evaluate the safety and effectiveness of plecanatide for the treatment of IBS-C.

To Learn more

CW ID: 213292
Date Last Changed: February 16, 2016

Clinical Trial Snapshot

Both Male and Female
18 to 85 Years
Overall Status
Lead Sponsor
Synergy Pharmaceutical
12 Weeks
Facility Type
Up to $300


Inclusion Criteria:

  • Patients with symptoms or a diagnosis of Irritable Bowel Syndrome with Constipation (IBS-C)

Exclusion Criteria:

  • Is on Linzess or Amitiza within 15 days of screening
  • Body Mass Index (BMI) <18 or >40 kg/m
  • History of IBD (e.g. Crohn's disease or Ulcerative Colitis)
  • History of a fecal impaction, requiring an intervention within the last 3 months
  • A medical illness that is predominantly characterized by chronic abdominal pain (e.g. untreated endometriosis, chronic ovarian cysts, painful menses, GERD, chronic pancreatitis)
  • History of or current structural abnormality of the GI tract or a disease that can affect GI motility (e.g. bowel obstruction, untreated abdominal adhesions, lactose intolerance, laxative or enema abuse, anal fissure)


Crystal Beaber, MA, CCRC, Senior Clinical Research Coordinator
Gastroenterology Associates of Tidewater
112 Gainsborough Square; Suite 200
Chesapeake, VA 23320
Phone: 757-547-0798; ext. 1131
Fax: 757-410-4123

View Map

Research Center Information:

Gastroenterology Associates of Tidewater

Volunteer for this Trial

If you would like to learn more about participating in this research study, please email the trial contact using the form below. We value your privacy and your information will only be used by the research center to contact you regarding this study.

DISCLAIMER: CenterWatch does not conduct clinical research. CenterWatch is a publishing company that posts clinical trials information on behalf of sponsor companies, contract research organizations, clinical research sites and other interested parties. This information is designed to help patients find clinical trials of interest and contact the research centers conducting the trials.