Clinical Trial Details


Research Study Summary

A double-blind, randomized, stratified, multi-center trial evaluating conventional and high dose oseltamivir in the treatment of immunocompromised patients with influenza


This 2-arm study will investigate the safety and tolerability of twice daily con ventional and double dose Tamiflu (oseltamivir) for the treatment of influenza i n immunocompromised patients. Eligible immunocompromised patients with laborator y-confirmed influenza will be randomized to receive either conventional dose (30 mg-75mg twice daily po, depending on age and weight) or double dose (60mg-150mg twice daily po depending on age and weight) Tamiflu for 10 days. Nasal and throa t swabs will be taken, and safety evaluations made, at intervals during the stud y. The anticipated time on study medication is 10 days and the anticipated time on study is 40 days.

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CW ID: 203046
Date Last Changed: December 10, 2014

Clinical Trial Snapshot

Both Male and Female
1 and up
Overall Status
Lead Sponsor
Facility Type


Sharon Porth
University of South Florida - Tampa General Hospital
1 Tampa General Circle
Tampa, FL 33606
Phone: (813)844-8249

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