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Therapeutic Areas: Oncology | Hematology
Disease Category: Acute Myelogenous Leukemia (AML)
Location: United States, CA

Trial Information

A Phase 1 Study of AC220 (ASP2689) as Maintenance Therapy in Subjects with Acute Myeloid Leukemia Who Have Been Treated with an Allogeneic Hematopoietic Stem Cell Transplant

The purpose of this study is:

  •  To determine the highest dose of AC220 that can be tolerated when given on a daily schedule after transplant.
  • To determine which side effects occur that prevent giving higher doses of AC220.
  • To evaluate if AC220 is effective at preventing or delaying return of disease.
  • To evaluate if there is difference in transplant related side effects in subjects who receive AC220.
  • To determine how AC220 is metabolized (how the body processes and eliminates the drug)
  • To explore how certain biomarkers are related to receiving AC220.

 

Patient Inclusion/Exclusion Criteria:


- See http://clinicaltrials.coh.org for additional information.


City of Hope
1500 East Duarte Road
Duarte, CA 91010-3000
Phone: 866-896-HOPE (4673)

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Research Center Information: City of Hope

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