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Therapeutic Areas: Oncology | Obstetrics/Gynecology (Women’s Health) | Family Medicine
Disease Category: Breast Cancer
Location: United States, IL

Clinical Trial Details


Research Study Summary

NSABP MA.32 Ancillary Study of Biobehavioral Mechanisms of Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin Hydrochloride Versus Placebo on NCIC-CTG-MA.32


This study is looking at whether Metformin, an agent that is commonly used to treat diabetes, can decrease or affect the ability of breast cancer cells to grow and whether Metformin will work with your other therapy to keep your cancer from recurring. Health Canada has not approved the sale or use of Metformin to treat breast cancer, although they have approved its use in this clinical trial. Although Metformin is approved by the FDA for the treatment of diabetes, its use in breast cancer is considered investigational.

Patient Inclusion Criteria:

  • Age ≥ 18 years
  • Patient must be eligible for randomization in the NCIC-CTG-MA.32 treatment trial for breast cancer
  • Patient must have completed primary breast radiotherapy at least two weeks prior to enrollment on NSABP-NCIC-CTG-MA.32.F and is not planning to receive radiotherapy after starting NCIC-CTG-MA.32
  • Hormone receptor status known

Patient Exclusion Criteria:

  • None of the following allowed:
    1. Patient must not have started taking NCIC-CTG-MA.32 study therapy

    To Learn more
  • Phase



    Both Male and Female


    18 and up

    Overall Status


    Facility Type



    Janeen V. Bazan, RN OCN BSN CCRP, Oncology Research Nurse Program Coordinator
    Sherman Health
    1425 North Randall Road
    Elgin, IL 60123
    Phone: 224-783-2907
    Fax: 224-783-3071

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    If you would like to learn more about participating in this research study, please email the trial contact using the form below.

    Zip/Postal Code:
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    CW ID: 183097

    Date Last Changed: July 17, 2013

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