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Therapeutic Areas: Cardiology/Vascular Diseases | Psychiatry/Psychology | Pulmonary/Respiratory Diseases
Disease Category: Smoking Cessation
Location: United States, NC

Clinical Trial Details


Research Study Summary

Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation (Durham and Raleigh, NC)


The purpose of this study is to look at brain function and attempt to predict which study drug or combination (nicotine patches, Chantix alone, or Chantix paired with Zyban) will be successful in helping individual smokers quit smoking.

This study consists of one physical screen, one fMRI training session, two fMRI scanning sessions, and seven study sessions over a 13-week period. The physical screen will take approximately 2-2 ½ hours and includes a drug screen. If you test positive for illegal drugs you will not be eligible to participate. You may also be asked to come in for a follow-up session six months after your quit day.

The fMRI training session will last approximately one hour, and the two fMRI scanning sessions will take approximately 1½ hours each. Each of the seven study sessions will last approximately 30 minutes.

If you complete all sessions and study requirements you will be compensated up to $460. You will receive a check in the mail after you complete study participation. Please allow four to six weeks for your payment to be processed. Subjects who qualify for, and come back in for a follow-up session six months after their quit day, will receive an additional $50 check in the mail. Payment for the follow-up session will be sent in a separate check four to six weeks after the session.

For further information or to participate in this study, please call 888-525-DUKE, or e-mail


To Learn more

Both Male and Female



Overall Status



13 Weeks

Facility Type



Up to $460


Duke CSC
3400 Executive Dr. Bld C, Ste 207
Raleigh, NC 27609
Phone: 1-888-525-3853

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Research Center Information: Duke CSC

If you would like to learn more about participating in this research study, please email the trial contact using the form below.

Zip/Postal Code:
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CW ID: 180961

Date Last Changed: July 19, 2013

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