Clinical Trial Details


Research Study Summary

Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation (Durham and Raleigh, NC)


The purpose of this study is to look at brain function and attempt to predict which study drug or combination (nicotine patches, Chantix alone, or Chantix paired with Zyban) will be successful in helping individual smokers quit smoking.

This study consists of one physical screen, one fMRI training session, two fMRI scanning sessions, and seven study sessions over a 13-week period. The physical screen will take approximately 2-2 ½ hours and includes a drug screen. If you test positive for illegal drugs you will not be eligible to participate. You may also be asked to come in for a follow-up session six months after your quit day.

The fMRI training session will last approximately one hour, and the two fMRI scanning sessions will take approximately 1½ hours each. Each of the seven study sessions will last approximately 30 minutes.

If you complete all sessions and study requirements you will be compensated up to $460. You will receive a check in the mail after you complete study participation. Please allow four to six weeks for your payment to be processed. Subjects who qualify for, and come back in for a follow-up session six months after their quit day, will receive an additional $50 check in the mail. Payment for the follow-up session will be sent in a separate check four to six weeks after the session.

For further information or to participate in this study, please call 888-525-DUKE, or e-mail


To Learn more

CW ID: 180961
Date Last Changed: July 19, 2013

Clinical Trial Snapshot

Both Male and Female
Overall Status
13 Weeks
Facility Type
Up to $460


Duke CSC
3400 Executive Dr. Bld C, Ste 207
Raleigh, NC 27609
Phone: 1-888-525-3853

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Research Center Information:

Duke CSC

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