Trial Information

BMT CTN 0702: A Trial of Single Autologous Transplant with or without Consolidation Therapy versus Tandem Autologous Transplant with Lenalidomide Maintenance for Patients with Multiple Myeloma

You are being asked to take part in this research study because you have multiple myeloma (MM), a cancer of the bone marrow. The study described in this consent form is designed to test different treatment strategies for multiple myeloma. Multiple myeloma is considered incurable. The standard therapy sometimes produces remission (absence of disease by standard clinical tests) in some individuals, but the disease recurs (returns) in all patients. This study will compare the time it takes for the disease to become active (progression-free survival) between the two single transplant groups (consolidation and maintenance only) and each of the two single transplant groups to the tandem transplant group. Additionally, this study will compare how the disease responds to each treatment after one year from entering the study and yearly thereafter. For individuals who have not achieved maximum response (complete response) by the time they start maintenance, the rate of achieving maximum response during maintenance will be evaluated and compared among the treatment groups. Additional comparisons and evaluation in this study include overall survival, whether a particular treatment prolongs more the survival than the other treatments, evaluation of the side effects, quality of life and incidence of infections in all three study treatments. Your participation in this study is expected to last an average of 4 years.

Patient Inclusion/Exclusion Criteria:

- See http://clinicaltrials.coh.org for additional information.

City of Hope
1500 East Duarte Road
Duarte, CA 91010-3000
Phone: 866-896-HOPE (4673)

View Map

Research Center Information: City of Hope

DISCLAIMER: This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials.