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Clinical Trial Details

Overview

Research Study Summary

Central Mechanisms that Regulate Glucose Metabolism in Humans

Purpose

Doctors at Albert Einstein College of Medicine are seeking people aged 21-60, with Type 2 diabetes, who are otherwise healthy, to participate in a medical research study to better understand how diazoxide, an FDA approved blood pressure medication, can regulate the production of sugar by the liver.

Inclusion Criteria:

  • BP < 130/90 (+-2 meds)
  • BMI < 35
  • Normal screening labs (CBC, chemistry, lft's PT/PTT)
  • No CAD
  • No first degree relatives with history of CAD or MI (men < 45; women < 55)
  • Good IV access
  • No other medical problems with exception: HTN (on < or = 2 meds), hypercholesterolemia, and stable retinopathy
  • Non-smoker
  • Hemoglobin A1C 7.5-11

Exclusion Criteria:

  • BP>130/90 (+- medications)
  • BMI > 35
  • Abnormal EKG
  • History of CAD or exertional chest pain
  • First degree relative with early CAD or MI
  • Medications for medical or psychiatric conditions including: dofetilide, fosphenytoin/phenytoin trichlormethiazide (any thiazide), chlorpromazine and warfarin
  • < 4 week history of participation in another drug trial

To Learn more

CW ID:165047
Date Last Changed: October 13, 2014

Clinical Trial Snapshot

Phase
2
Gender
Both Male and Female
Age
N/A
Overall Status
Recruiting
Facility Type
N/A

Contact

Morgan Drucker, Research Coordinator
The Harold & Muriel Block Institute for Clinical and Translational Research at Einstein & Montefiore
Albert Einstein College of Medicine/Montefiore Medical Center
1300 Morris Park Avenue
Bronx, NY 10461
Phone: 718-430-2903

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