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Therapeutic Areas: Endocrinology | Family Medicine
Disease Category: Diabetes Mellitus, Type 2
Location: United States, NY

Clinical Trial Details

Overview

Research Study Summary

Central Mechanisms that Regulate Glucose Metabolism in Humans

Purpose

Doctors at Albert Einstein College of Medicine are seeking people aged 21-60, with Type 2 diabetes, who are otherwise healthy, to participate in a medical research study to better understand how diazoxide, an FDA approved blood pressure medication, can regulate the production of sugar by the liver.

Inclusion Criteria:

  • BP < 130/90 (+-2 meds)
  • BMI < 35
  • Normal screening labs (CBC, chemistry, lft's PT/PTT)
  • No CAD
  • No first degree relatives with history of CAD or MI (men < 45; women < 55)
  • Good IV access
  • No other medical problems with exception: HTN (on < or = 2 meds), hypercholesterolemia, and stable retinopathy
  • Non-smoker
  • Hemoglobin A1C 7.5-11

Exclusion Criteria:

  • BP>130/90 (+- medications)
  • BMI > 35
  • Abnormal EKG
  • History of CAD or exertional chest pain
  • First degree relative with early CAD or MI
  • Medications for medical or psychiatric conditions including: dofetilide, fosphenytoin/phenytoin trichlormethiazide (any thiazide), chlorpromazine and warfarin
  • < 4 week history of participation in another drug trial

To Learn more
Phase

2

Gender

Both Male and Female

Age

N/A

Overall Status

Recruiting

Facility Type

N/A

Contact

Sara Reda, BS, Research Coordinator
The Harold & Muriel Block Institute for Clinical and Translational Research at Einstein & Montefiore
Albert Einstein College of Medicine/Montefiore Medical Center
1300 Morris Park Avenue
Bronx, NY 10461
Phone: 718-430-2903

View Map

CW ID: 165047

Date Last Changed: March 21, 2014


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