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Therapeutic Areas: Otolaryngology (Ear, Nose, Throat) | Pulmonary/Respiratory Diseases | Immunology | Infections and Infectious Diseases
Disease Category: Allergy
Location: United States, NY
Diagnosis of Aspirin Hypersensitivity by Measuring Arachidonic Acid Metabolites after Low Dose Aspirin Challenge
This is a research study of a new approach to diagnose aspirin allergy. Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is frequently reported by patients requiring aspirin (ASA) for coronary artery disease or NSAIDs for pain management. Even though clinical challenge with relatively high doses of aspirin carries a substantial risk of severe reactions in ASA-hypersensitive population (e.g., bronchospasm), it is used as a gold standard to confirm the diagnosis of ASA hypersensitivity (AH) . A safer, more time and cost efficient test to diagnose ASA-hypersensitivity would be useful.
CW ID: 164960
Date Last Changed:
July 23, 2013
Elina Jerschow, MD, Principal InvestigatorThe Harold & Muriel Block Institute for Clinical and Translational Research at Einstein & MontefioreAlbert Einstein College of Medicine/Montefiore Medical Center
1515 Blondell Ave., Suite 220Bronx, NY 10461Phone: 866-MED-TALK
The Harold & Muriel Block Institute for Clinical and Translational Research at Einstein & Montefiore
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