Clinical Trial Details


Research Study Summary

Preventing the Recurrence of Depression in Bipolar Disorder


This study compares combination treatment with a mood stabilizer plus an antidepressant to treatment with the mood stabilizer alone and to gather information about the safety, tolerability and frequency of mood changes during continuation treatment. The purpose is to collect information about whether the combination treatment results in fewer returns of depressive symptoms compared to treatment with the mood stabilizer alone. Both study drugs are FDA-approved. Study participation can last up to 62 weeks.

Inclusion Criteria

  • Men and women
  • 18 years of age or older
  • Diagnosis of bipolar disorder, currently experiencing a depressive episode
  • Able to read, write and understand English

Exclusion Criteria

  • Current alcohol or drug abuse, or alcohol or drug dependence within the past 3 months
  • Known sensitivity to (or unable to take) either study drug
  • Unstable medical condition or use of certain other medications
  • Pregnant or nursing women, or women of child-bearing potential who are unwilling to use a medically acceptable form of contraception
  • Actively suicidal or requiring hospitalization

To Learn more

CW ID: 164482
Date Last Changed: July 24, 2013

Clinical Trial Snapshot

Both Male and Female
18 and up
Overall Status
62 Weeks
Facility Type


Linda Skaggs
Rush University Medical Center - Treatment Research Center
1700 W. Van Buren Street, 5th Floor
Chicago, IL 60612
Phone: 312-980-6356
Fax: 312-942-2177

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Volunteer for this Trial

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