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Therapeutic Areas: Endocrinology
Disease Category: Hypogonadism
Trial Information
Role of Gonadotropin Pulsations in the Reversal of Hypogonadotropic Hypogonadism
The purpose of the research study is to examine how Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH) affect reproductive hormones. These disorders are caused by a defect in Gonadotropin Releasing Hormone (GnRH) secretion. GnRH is a hormone released by a small gland in the brain called the hypothalamus. When GnRH is released, it signals another gland in the brain, the pituitary, to secrete the reproductive hormones that influence testosterone levels and reproductive function.
This study involves a detailed evaluation which involves an overnight stay at the hospital.
Eligibility Criteria:
Adult men and women 18+ yrs
Adolescent boys 16+ yrs
Individuals with IHH and KS:
1) have abnormally low hormone levels
2) may have not gone through a normal puberty
3) often have infertility
Andrew Dwyer, RN, MSN
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114
Phone: 617-726-8622
EMail: Adwyer@partners.org
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If you would like to learn more about participating in this study, please send an e-mail message using the form below.
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