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Therapeutic Areas: Neurology | Psychiatry/Psychology
Disease Category: Memory Loss
Trial Information
Does Memantine Improve Verbal Memory Task Performance in Subjects with Left Temporal Lobe Epilepsy and Memory Dysfunction? A Randomized, Double-Blind, Placebo-Controlled Trial.
Does memantine improve verbal memory task performance in patients with left temporal lobe epilepsy and memory dysfunction? A randomized, double-blind, placebo-controlled trial.
Many patients with epilepsy have memory deficits. Unfortunately, the treatment options for memory dysfunction in patients with epilepsy are limited. We are conducting a study to evaluate the effects of memantine, a medication used for the treatment of Alzheimer’s Disease, for the treatment of verbal memory dysfunction in subjects with left temporal lobe seizures. The study involves randomization to memantine therapy or placebo, with cognitive testing and EEG pre- and post-treatment.
All subjects must:
•Be 18-55 years of age
•Have left temporal lobe seizures
•Be native English-speaking
•Be able to give consent
•Have self-reported memory dysfunction
Participation will require two study visits over the 13-week duration of the trial. Each subject will be offered $100 dollars for participation, parking and meal vouchers, as well as free study medication during the trial.
If you or your doctor feel that you might be a candidate for this study, or if you wish to obtain more information, please contact:
Beth Leeman, M.D.
Phone: 617-726-3311
E-mail: baleeman@partners.org
Christine M Arsnow
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114
Phone: 781-864-6525
EMail: carsnow@partners.org
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If you would like to learn more about participating in this study, please send an e-mail message using the form below.
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