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Therapeutic Areas: Psychiatry/Psychology
Disease Category: Depression (Major/Severe)

Trial Information

Efficacy and safety study of adjunctive AZD6765 in subjects with severe Major Depressive Disorder and a history of poor response to antidepressants

Investigational medication administered intravenously in patients with Major Depressive Disorder and a history of poor response to antidepressants. This is a double blind, randomized, parallel group, placebo controlled study.

Inclusion Criteria

• Male or female 18-65 years
• Diagnosis of MDD or single episode MDD
• Currently taking one FDA approved antidepressant for at least 6 weeks
• History of poor response to one or more antidepressants

Exclusion Criteria

• Comorbid panic or simple phobias, schizophrenia, bipolar, psychosis, or psychotic depression are excluded.
• Current episode of depression < 12 weeks
• Use of mood stabilizers, antipsychotics, TCA, or MAOIs
• Failure to ECT
• Vagal nerve stimulation
• History of substance abuse

Danette Beard, LPN
Lake Charles Clinical Trials
2770 3rd Avenue, Suite 340
Lake Charles, LA 70601
Phone: 337 494-3266
Fax: 337 494-2089

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