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Therapeutic Areas: Immunology/Infectious Diseases | Dermatology/Plastic Surgery
Disease Category: Herpes Zoster Infections

Trial Information

Clinical trial of an investigational vaccine for the prevention of shingles and shingles-related complications in immunocompromised individuals

A Phase I, Double-Blind, Randomized, Placebo-Controlled, Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults

Ages Eligible for Study: 18 Years and older
Genders Eligible for Study: Both
Accepts Healthy Volunteers: No

Criteria

Inclusion Criteria:

  • Men and women 18 years of age or older
  • Patients who are scheduled to receive an autologous or allogeneic hematopoietic cell transplant within 60 days of enrollment
  • HIV-infected patients with a baseline CD4 cell count < or = to 200 cells/mm3
  • Patients with hematologic malignancies
  • Patients who are receiving chemotherapy for breast, colorectal, or lung malignancies

Exclusion Criteria:

  • History of allergy to any vaccine component
  • Prior history of herpes zoster
  • Prior history of receipt of any varicella or zoster vaccine

Merck
Located in:
Newark, NJ 07103
Phone: 1-888-577-8839

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