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Therapeutic Areas: Nephrology/Urology
Disease Category: Kidney Disease
Trial Information
Reduced Phosphate Intake in 'Normo-Phosphatemic' Chronic Kidney Disease Patients
We would like to study the role of phosphorous metabolism in the development of certain hormonal problems in people with Chronic Kidney Disease. More specifically, the goals of the research are (1) to understand the cause of hyperparathyroidism – a hormone problem that often develops in patients who have kidney disease and (2) to test whether decreasing phosphorus intake could help improve or prevent hyperparathyroidism. Eligible subjects will be people with reduced kidney function who are 18 years of age or older. Subjects will have nine visits over approximately one month. For two weeks during this time, subjects will consume a controlled phosphorus diet provided by the clinical research center. Some subjects will be prescribed a phosphorus binding tablet to limit the absorption of phosphorus in the gut. Subjects will be compensated for completing the protocol.
Please contact Mike at (617) 724-3416 for more information.
Michael Epstein
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114
Phone: 617-724-3416
EMail: mepstein1@partners.org
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