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Therapeutic Areas: Oncology | Nephrology/Urology
Disease Category: Renal Cell Carcinoma

Trial Information

Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma

The purpose of this study is to determine if either Sunitinib or Sorafenib can prevent recurrence of kidney cancer and to compare the effects (both good and bad) of the Sunitinib and the Sorafenib with Placebo (pills that look like the study drugs, but are inactive or do not contain the drug) on the patient and the patient's kidney cancer to see which is better.

Patient Inclusion Criteria:

  • Renal (Kidney) cell carcinoma eligible for nephrectomy with curative intent
  • Age > 18 years
  • No prior cancers within 5 years
  • No serious intercurrent illness

Patient Exclusion Criteria:

  • Hypertension (elevated bldoo pressure) not controlled with medications
  • HIV positive

Primary Outcomes: To demonstrate an improvement in disease-free survival in locally advanced renal cell carcinoma

Key Secondary Outcomes: To compare overall survival between the two regimens

Janeen V. Bazan, Oncology Research Nurse Program Coordinator
Sherman Health Systems
934 Center Street
Elgin, IL 60120
Phone: (847) 429-2907
Fax: (847) 429-3071
EMail: janeen.bazan@shermanhospital.org

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Research Center Information: Sherman Health Systems

If you would like to learn more about participating in this study, please send an e-mail message using the form below.

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