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Therapeutic Areas: Musculoskeletal
Disease Category: Lower Back Pain
Trial Information
Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
Duloxetine has recently been shown to be effective in reducing
the pain in chronic pain patients. Duloxetine is known to exert a
central mechanism, however the precise human brain structures
responsible for mediating its pain-relieving properties are not
known. We will use functional magnetic resonance imaging (fMRI) to
investigate the neural and functional correlates of pain.
Patient Inclusion Criteria:
- Males aged 18-60
- Currently have low back Pain
- Must be able to comply with study visit schedule and other
study requirements
- Capable of performing the experimental tasks
Patient Exclusion Criteria:
- Contraindications for MRI examination (e.g., metallic implants
such as pacemakers, surgical aneurysm clips, or known metal
fragments embedded in the body)
- Known hypersensitivity to duloxetine or any of the inactive
ingredients
- Uncontrolled narrow-angle glaucoma
Uta Maeda
Stanford University School of Medicine
Stanford Systems Neuroscience and Pain Lab
780 Welch Road #109
Palo Alto, CA 94304
Phone: 650-724-0522
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