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Therapeutic Areas: Oncology
Disease Category: Thyroid Cancer

Trial Information

A Multicenter, Open-Label, Randomized, Phase II/III Study to Evaluate the Safety and Efficacy of Combretastatin A-4 Phosphate in Combination with Paclitaxel and Carboplatin in Comparison with Paclitaxel and Carboplatin Against Anaplastic Thyroid Carcinoma (OXC4T4)

Primary objective is to compare the antineoplastic efficacy of CA4P + paclitaxel + carboplatin+ with paclitaxel + carboplatin against ATC by measuring overall survival.

Secondary objectives are:

  • To evaluate the safety and tolerability of the triple combination of CA4P + paclitaxel + carboplatin
  • To assess specified objective events: tracheostomies, PEG tube placements, and weight loss

See www.hsc.wvu.edu/mbrcc/ctru/ for additional information.

Dr. John Naim
West Virginia University - Clinical Trials Research Unit
1637 Health Sciences South, PO Box 9260
Morgantown, WV 26506
Phone: 304-293-7374

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