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Seattle, Washington Clinical Trials

A listing of Seattle, Washington clinical trials actively recruiting patient volunteers.

RESULTS

Found (13) clinical trials

A Placebo-Controlled Effectiveness in INPH Shunting (PENS) Trial

The primary intervention will be setting the FDA-approved Certas Plus with Siphonguard, programmable CSF shunt valve to active (open shunt group)(setting 4)(110 mm H2O) or placebo (closed shunt group)(setting 8)(>400 mm H2O)in a 1:1 ratio. By the time of the primary objective evaluation at four months, the closed shunt group ...

Phase N/A

0.0 miles

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A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies

This is a Phase 1, open-label, 3 + 3 dose escalation study to determine the safety and preliminary efficacy of voruciclib in subjects with relapsed/refractory B cell malignancies after treatment with standard therapy. There will be up to 5 dose level cohorts. Up to 6 subjects will be enrolled per ...

Phase

0.35 miles

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Neihulizumab (AbGn-168H) in Patients With Steroid-refractory Acute Graft-versus-host Disease

This study is a Phase I, single dose, dose-escalation study to study the pharmacokinetics, safety, signs of efficacy, receptor occupancy and pharmacodynamics biomarkers (REG3-alpha and ST2 of Neihulizumab in patients with steroid-refractory acute GvHD. Up to 24 patients will be recruited in 4-9 clinical centers in US.

Phase

2.05 miles

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Durvalumab Tremelimumab and Stereotactic Body Radiation Therapy in Treating Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

PRIMARY OBJECTIVES: I. To demonstrate safety and tolerability of durvalumab and tremelimumab and palliative radiation therapy in patients with recurrent metastatic squamous cell carcinomas of the head and neck previously exposed to an anti PD-1 or PDL-1 monoclonal antibody. SECONDARY OBJECTIVES: I. Measure objective response rates based on Response Evaluation ...

Phase

2.05 miles

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Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant

PRIMARY OBJECTIVES: I. Determine whether 2-5 year hematopoietic cell transplant (HCT) survivors with elevated cancer-related distress or poor health care adherence, adherence to cardiometabolic or subsequent malignancy surveillance who are randomized to receive the online, patient-centered, self-management stepped care program will report reduced distress, and improved health care adherence for ...

Phase N/A

2.05 miles

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Randomized Trial to Reduce Mental Health Disparities in Latina Immigrant Women

The proposed study aims to test the efficacy of the Amigas Latinas Motivando el Alma (ALMA) intervention in a randomized control trial. ALMA is an 8-week program offered in a group format to teach women new coping strategies and enhance their social ties and social support to prevent and reduce ...

Phase N/A

2.1 miles

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Auto Control of Volume Management for Limb Loss

People with lower limb amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb health problems including skin breakdown and injury to deeper tissues. Prosthetic socket systems that accommodate limb volume changes ...

Phase N/A

3.69 miles

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Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex

This study estimates the incidence of postoperative residual neuromuscular block when rocuronium neuromuscular block is managed by protocol for qualitative monitoring and reversal with neostigmine or sugammadex. The study is an extension of the recently published study by Thilen and co-workers which evaluated a protocol which used neostigmine as the ...

Phase N/A

3.69 miles

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Rolandic Epilepsy Genomewide Association International Study

Epilepsy is a common neurological disorder affecting 1% of the population. There are over 30 types of epilepsy, some common, some rare. Most epilepsies arise in childhood and have a genetic cause. Approximately 25% of child patients have "Rolandic Epilepsy" or RE, also known as Benign Epilepsy with Centrotemporal Spikes ...

Phase N/A

4.18 miles

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An Investigational Immuno-therapy Study of Nivolumab Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma

The purpose of this study is to evaluate the safety and effectiveness of several combination therapies for Multiple Myeloma. Upon entry into the study, patients will be randomized (assigned by chance) to receive either: Group 1: nivolumab, pomalidomide and dexamethasone OR Group 2: pomalidomide and dexamethasone OR Group 3: nivolumab, ...

Phase

4.57 miles

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