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Research Triangle Park, North Carolina Clinical Trials

A listing of Research Triangle Park, North Carolina clinical trials actively recruiting patient volunteers.

RESULTS

Found (284) clinical trials

Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy System

This is a multi-center randomized study of three doses of radiation (assigned 1:1:1) delivered by the TheraSight(TM) Brachytherapy System in participants with choroidal neovascularization (CNV) secondary to wet (exudative) AMD. Each participant receives a single dose of radiation delivered by one-time only brachytherapy. Participants are followed for three years after ...

Phase

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Environmental Polymorphisms Registry

We are establishing a registry-based cohort and repository of biological (e.g. blood, urine,saliva, etc.) and environmental (e.g. household dust) specimens (approximately 20,000 participants) in which the donated specimens are linked to the donor s identities, contact information, and some basic demographics through a personal identification number (PIN). Specimens are available ...

Phase N/A

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Immune Cell Response to Stimuli

The objective is to define the signaling pathways activated by lipopolysaccharide (LPS) and other selected innate immunity stimuli, and the downstream inflammatory functional consequences, in human leukocytes in vitro. Adult (greater than or equal to 18 - 65 years old), nonpregnant, healthy volunteers will have 320 ml of whole blood ...

Phase N/A

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Environmental Risk Factors for the Anti-synthetase Syndrome

Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Based on prior studies suggesting roles for noninfectious and infectious agents in the development of myositis, as well as the known clinical, epidemiologic and genetic differences ...

Phase N/A

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Bisphenol A Controlled Exposure Study

Bisphenol A (BPA) is utilized primarily in the manufacture of polycarbonate plastic and epoxy resins, which are widely used in the fabrication of baby bottles and food can linings. Consequently, human exposures to BPA are widespread. However, there is still uncertainty about the extent and nature of these exposures. This ...

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TGF-(Beta) and Susceptibility to RSV

This is a cross-sectional, controlled study designed to investigate whether Transforming Growth Factor-beta (TGF-beta) mediates increased asthmatic epithelial susceptibility to respiratory syncytial virus (RSV) infection by examining responses to RSV infection in epithelial cells cultured from asthmatic and non-asthmatic participants. Non-smoking healthy adults and mild asthmatics, aged 18-60 years old, ...

Phase N/A

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Study of Exposure to Chemicals in Consumer Products

Research to advance the characterization of environmental and chemical exposures through improved exposure assessments, at both the individual and population levels, is a research priority identified in the Strategic Research Action Plan for the U.S. Environmental Protection Agency (EPA) s Chemical Safety for Sustainability (CSS) program (EPA 2012) and the ...

Phase N/A

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Mobile Technology and Online Tools to Improve Asthma Control in Adolescents - Usability

This project will fully develop and preliminarily validate CampAir, an empirically-based dynamic e-health intervention (based on the evidence-based ASMA) to assist adolescents with uncontrolled asthma to learn how to manage their illness and improve their asthma control. In addition to developing a highly novel product for adolescents with asthma, the ...

Phase

3.14 miles

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Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients

The study will consist of the following periods: Screening (Days -21 to -1), Transplant (Day 0), Post-Transplant (Day 0/post-skin closure through 12 months post-transplant). All subjects will enter into a Screening Period (Days -21 to -1 prior to transplant), undergo a Transplant (Day 0 [zero]), and are then to be ...

Phase

3.14 miles

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Arise: An Online Relapse Prevention Tool for Adolescent Substance Abusers

Purpose: In Phase I of this SBIR project, 3C Institute (3C) developed a working prototype of For Life (henceforth Arise), an innovative computer-based coping skills educational program for adolescent substance abuse treatment completers. For Phase I, 3C developed and tested two customizable intelligent educational modules to teach coping skills in ...

Phase

3.14 miles

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