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Wheaton, Maryland Clinical Trials

A listing of Wheaton, Maryland clinical trials actively recruiting patient volunteers.

RESULTS

Found (11) clinical trials

Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation

We propose a longitudinal study of the natural history of the collagen-related disorder osteogenesis imperfecta (OI). The overall objectives are to 1) obtain a comprehensive assessment of the natural history and progression of the multiple secondary features of osteogenesis imperfecta, and 2) further the understanding of genotype-phenotype correlation using biosamples ...

Phase N/A

3.66 miles

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Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B

Up to 300 subjects with hepatitis B e antigen (HBeAg) negative chronic hepatitis B who are inactive carriers (specified as those with HBV DNA levels <2,000 IU/ml over a 6-month period with ALT levels <1.5 X upper limit of normal and HBsAg level <1500 U/mL) will be screened and 25 ...

Phase

3.66 miles

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Focus Groups to Determine Surrogates Views Regarding Patient Preference Predictors

Current clinical practice relies on shared decision-making between clinicians and surrogates to make treatment decisions for patients who cannot decide on their own. This decision-making process is meant to promote medical care that accords with the patient s own preferences and values. However, empirical data suggest that this model faces ...

Phase N/A

3.66 miles

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A Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) in Combination With Rituximab Cyclophosphamide Doxorubicin Vincristine and Prednisone in Patients With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma

This is a randomized (individuals assigned to study treatment by chance), double-blind (individuals and study personnel will not know the identity of study treatments), placebo (an inactive substance that is compared with a drug to test whether the drug has a real effect in a clinical trial)-controlled study to compare ...

Phase

3.66 miles

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PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

Background: An extensive body of literature points towards neuronal brain injury in human immunodeficiency virus positive (HIV-positive) subjects despite virological suppression of the virus in the periphery under the effect of antiretroviral therapies (ART). Existing evidence suggests that the central nervous system (CNS) could be an important reservoir for human ...

Phase N/A

3.66 miles

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Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

The purpose of this protocol is to develop and test new MRI techniques applicable to patients undergoing cardiovascular evaluation with the ultimate goal of translating the technical advances into improving clinical diagnosis and management of patients undergoing cardiovascular evaluation. Patients undergoing cardiovascular evaluation and healthy volunteers will be scanned under ...

Phase N/A

3.66 miles

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First-in-human Study of BAY2287411 Injection a Thorium-227 Labeled Antibody-chelator Conjugate in Patients With Tumors Known to Express Mesothelin

The primary objective of this study is, to determine the safety, tolerability, maximum tolerated dose (MTD) or maximum feasible dose of BAY2287411 Injection in patients with epithelioid malignant mesothelioma and serous ovarian cancer

Phase

3.66 miles

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Study of Efficacy and Safety in Premenopausal Women With Hormone Receptor Positive HER2-negative Advanced Breast Cancer

The purpose of this study is to assess the efficacy of LEE011, as measured by progression free survival (PFS), in premenopausal women with HR positive, HER2 negative advanced breast cancer

Phase

4.62 miles

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Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

Over 180,000 diagnoses of invasive breast cancer are made in the US each year. Over onethird of women with early stage and over half with latestage breast cancer are treated with mastectomy (removal of the entire breast) due to tumor size, multiple cancers within the breast, genetic cancer predisposition, and/or ...

Phase N/A

7.22 miles

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A Nutrition Intervention for Arthritis -4 (WCCR-ARTH4)

Preliminary evidence suggests that low-fat, vegetarian diets and certain nutritional supplements can help reduce pain and also reduce the need for pain medications for some people. The investigators will ask about 100 people to participate. All of them will get a low-fat, vegan diet and a nutritional supplement (mixture of ...

Phase N/A

7.22 miles

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