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Johns Creek, Georgia Clinical Trials

A listing of Johns Creek, Georgia clinical trials actively recruiting patient volunteers.

RESULTS

Found (105) clinical trials

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

The study will investigate the antidepressant effects of a range of doses of JNJ-42847922 (seltorexant) (versus placebo), as adjunctive treatment to antidepressant drugs for treatment of MDD, and will assess the safety and tolerability of JNJ-42847922. The study will be conducted in 3 phases: a screening phase (up to 4 ...

Phase

2.5 miles

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Evaluate Safety and Tolerability of Calcipotriene Foam 0.005% in Pediatric Subjects With Mild/Moderate Plaque Psoriasis

This is a multicenter, open-label, Phase 1 study in a total of 75 pediatric subjects, ages 2 to 11 years, inclusive, with mild or moderate plaque psoriasis. The study will enroll sufficient subjects with plaque psoriasis and an ISGA score of mild to moderate (score of 2 or 3) at ...

Phase

2.5 miles

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This Phase 3 study is intended to provide evidnece of the efficacy and safety of study drug when dosed twice a day in adult patients with moderate to severe Rheumatoid Arthritis. It is intended to confirm the benefits of study drug in improving signs and symptoms and physical function that ...

Phase

2.5 miles

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24-Week trial comparing treatment with Study Medicine vs. placebo. Patient Inclusion Criteria: Age >/= 18 Diagnosis of definite AS Active AS Inadequate response to treatment. Patient Exclusion Criteria: Major Surgery within 8 weeks prior to screening Inflammatory Disease other than AS Treatment with Investigational Medication within 4 weeks Hepatitis B, ...

Phase

2.5 miles

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A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Study Of Study Medicine On Peripheral Nerve Function In Patients With Osteoarthritis Patient Inclusion Criteria: BMI less or equal to 39 kg/m2 Osteoarthritis (arthritis) of the knee or hip with pain score that qualifies Patient Exclusion Criteria: Untreated, uncontrolled diseases, Unwilling or unable ...

Phase

2.5 miles

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This study is designed to evaluate safety and assess initial efficacy of Study Medication, a JAK3 inhibitor, for treatment of subjects with active RA. This study will assess the clinical response of 4 doses of Study Medication compared to placebo when administered for 12 weeks to patients with active RA. ...

Phase

2.5 miles

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A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE) Patient Inclusion Criteria: Clinical diagnosis of SLE by American College of Rheumatology (ACR) criteria Have positive antinuclear antibodies (ANA) Agree not to become pregnant ...

Phase

2.5 miles

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A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy Patient Inclusion Criteria: Diagnosis of Rheumatoid Arthritis (RA) of more than 6 months and less than 15 years ...

Phase

2.5 miles

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The purpose of the study is to evaluate the effectiveness of two dosing regimens of Investigational Product (Oral Agent) compared to placebo, in patients with rheumatoid arthritis (RA). Patient Inclusion Criteria: Active rheumatoid arthritis (RA) diagnosed after the age of 16 6 or more swollen joints and 6 or more ...

Phase

2.5 miles

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A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Investigational Product in Patients With Non-Cancer-Related Pain and Opioid-Induced Constipation (OIC) Patient Inclusion Criteria: Provision of written informed consent prior to any study-specific procedures. Self-reported active symptoms of OIC at screening ( Receiving a stable maintenance opioid regimen ...

Phase

2.5 miles

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