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Wimbledon, United Kingdom Clinical Trials

A listing of Wimbledon, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (13) clinical trials

A Study to Evaluate the Pharmacokinetics Efficacy and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast Cancer

This is a global Phase III, two-arm, open-label, multicenter, randomized study to investigate the pharmacokinetics, efficacy, and safety of the fixed-dose combination (FDC) of pertuzumab and trastuzumab for subcutaneous (SC) administration in combination with chemotherapy in patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer in the ...

Phase

2.02 miles

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Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

The objective of this study is to evaluate the effect of multiple doses of vericiguat on the QTc interval in patients with stable CAD (coronary artery disease).

Phase

2.14 miles

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Rolandic Epilepsy Genomewide Association International Study

Epilepsy is a common neurological disorder affecting 1% of the population. There are over 30 types of epilepsy, some common, some rare. Most epilepsies arise in childhood and have a genetic cause. Approximately 25% of child patients have "Rolandic Epilepsy" or RE, also known as Benign Epilepsy with Centrotemporal Spikes ...

Phase N/A

6.57 miles

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Investigating Attention Patterns in Young People With Anxiety

Adolescents with elevated anxiety have been found to direct their voluntary and involuntary attention more readily toward threatening stimuli, and spend more time dwelling upon that stimuli. Various computerised tasks have been developed to attempt to retrain these "attention biases" back away from threat. This study will test a newly ...

Phase N/A

6.69 miles

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Investigating the Physiological Effects of Weight Loss on Male Fertility

Please contact study staff for a detailed description.

Phase N/A

6.81 miles

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Effect of Fibre Supplements on Gestational Diabetes

Aim: To evaluate the effect of a soluble fibre supplement in glucose metabolism in pregnant women at high risk of developing gestational diabetes. Study methodology: 12 week randomised, placebo-controlled, single-blinded study. Intervention: Women will first be categorised according to their glycaemic status into two groups: GDM and glucose tolerant women. ...

Phase N/A

6.87 miles

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Follow up of LEAP Participants and Their Families

Background: Food allergies and peanut allergy (PA) are becoming increasingly common conditions and are an important public health concern. Dietary avoidance of peanut in early life has been recommended in many countries. However, there is evidence that the prevalence of PA is decreased in countries where children are fed peanut ...

Phase N/A

7.01 miles

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A Study of TAS0728 in Patients With Solid Tumors With HER2 or HER3 Abnormalities

This is a First-in-Human (FIH), 2-part, Phase 1/2, open-label, multicenter study design to evaluate the safety, tolerability, PK, pharmacodynamics, PGx, and efficacy of TAS0728. This study consists of Phase 1 and Phase 2a components in subjects with advanced solid tumors with HER2 or HER3 overexpression, amplification, or mutation who have ...

Phase

7.73 miles

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STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity

This study will look at the change in participants' body weight from the start to the end of the study. The weight loss in participants taking semaglutide (a new medicine) will be compared to the weight loss of participants taking "dummy" medicine. In addition to taking the medicine, participants will ...

Phase

8.08 miles

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A First-In-Human Study of Orally Administered JNJ-64417184 to Evaluate the Safety Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses and the Antiviral Activity of Multiple Doses in a Respiratory Syncytial Virus (RSV) Challenge Study in Healthy Participants

The purpose of the study is to evaluate the safety and tolerability of single and multiple oral doses of JNJ-64417184 administered to healthy participants and the antiviral effect of multiple oral doses of JNJ-64417184 compared to placebo in participants infected through inoculation with respiratory syncytial virus (RSV)-A Memphis 37b (Part ...

Phase

8.1 miles

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