Search Medical Condition
Please enter condition
Please choose location

Ruddington, United Kingdom Clinical Trials

A listing of Ruddington, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (114) clinical trials

A Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of JNJ-48816274

This is a 3-part study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of JNJ-48816274 in healthy participants after administration of single and repeated doses, and to evaluate its potential effectiveness for treating insomnia.

Phase

0.92 miles

Learn More »

A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants

This open-label, randomized, 4-way crossover study in healthy participants will determine the relative bioavailability of the tablet formulation relative to the capsule formulation and the effect of a high-fat and low-fat meal on the relative bioavailability of the tablet formulation.

Phase

0.92 miles

Learn More »

First-in-Human Single and Multiple Dose of EB8018

Crohn's Disease is a chronic inflammatory disease of the gastrointestinal tract. Emerging evidence suggests that the microbiome plays an important role in triggering an abnormal mucosal immune response in patients with Crohn's Disease. Independent studies have demonstrated an imbalance of the microbiome with a significant increase of E coli with ...

Phase

0.92 miles

Learn More »

A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers

For Parts 1, 2 and 3, participants will attend the clinical unit for a screening visit up to 28 days before dosing. For each treatment period, eligible subjects will be admitted to the clinical unit on the evening before dosing (Day -1). Participants will receive each regimen in the morning ...

Phase

0.92 miles

Learn More »

First in Human Single Ascending Dose Study of MOR107

MOR107 is an angiotensin 2 receptor (AT2R) agonist with the potential to treat a wide range of diseases through activation of the protective arm of the renin-angiotensin system. In this study MOR107 will be administered to humans for the first time. The study will enroll healthy male subjects and is ...

Phase

0.92 miles

Learn More »

Study to Compare the Pharmacokinetics and Pharmacodynamics of 6 mg RGB-02 to 6 mg Neulasta

Single-centre, double-blind, randomised, two-period, two-way crossover study to investigate the pharmacokinetics and pharmacodynamics of RGB-02 as compared to Neulasta® administered as a single subcutaneous injection in healthy adult subjects.

Phase

0.92 miles

Learn More »

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

This study will evaluate the pharmacokinetics and safety of GDC-0134 in healthy female volunteers of non-childbearing potential. The first part of the study will compare the bioavailability of a prototype capsule of GDC-0134 relative to an existing GDC-0134 reference capsule (Periods 1 and 2). The second part of the study ...

Phase

0.92 miles

Learn More »

Impact of Changing the Dosing Regimen on the PK Profile of ODM-203

This study will be a single dose part randomised cross over study with up to 6 study periods. ODM-203 may be dosed using a variety of different conditions with respect to food depending on emerging data. The impact of changing the presentation of ODM-203 may also be assessed to determine ...

Phase

0.92 miles

Learn More »

A Study to Compare the Pharmacokinetics of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule Relative to an Immediate Release (IR) Tablet Formulation and to Investigate the Pharmacokinetics of a Selected MR Formulation in Capsule Following Repeat Doses

This study will evaluate the pharmacokinetics of GSK2982772 following administration of modified release formulations in a capsule relative to an immediate release reference tablet formulation and the pharmacokinetics of escalating repeat doses of a selected modified release prototype. The study is divided into two parts: Part A will be a ...

Phase

0.92 miles

Learn More »

A Study to Investigate the Effect of Formulation Food and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants

The purpose of this study is to evaluate the PK of GDC-0853 following changes to formulation and in the presence or absence of food, the proton pump inhibitor (rabeprazole), or both. This will be a 3-part open-label randomized study conducted in healthy adult participants. Approximately 63 subjects will be enrolled ...

Phase

0.92 miles

Learn More »