Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters
 

Northwick Park, United Kingdom Clinical Trials

A listing of Northwick Park, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (82) clinical trials

Safety and Tolerability of MEDI3506 in Healthy Subjects in Subjects With COPD and Healthy Japanese Subjects

This is a Phase 1, randomised, blinded, placebo controlled, study designed to evaluate the safety, tolerability, pharmacokinetics, and immunogenicity response to single and multiple doses of MEDI3506 administered by either SC or IV routes. Part I: Single Ascending Doses in Healthy Subjects with a History of Mild Atopy Part II: ...

Phase

0.13 miles

Learn More »

Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

This study will be an open-label, randomized, 3-period, 3-treatment, single-dose crossover study in healthy subjects (males and females), performed at a single study center, conducted in 3 cohorts. A total of 126 healthy male or female subjects (3 cohorts of 42 subjects each [each cohort consisting of 3 treatments]) will ...

Phase

0.13 miles

Learn More »

A Phase I Study to Assess the Safety Tolerability Pharmacokinetics Pharmacodynamics and Food Effect of AZD9898

This study will be a Phase I, randomized, placebo-controlled study in healthy subjects and asthma patients, performed at 2 study centers. The study will consist of 3 parts (Part 1 [SAD in healthy subjects]; Part 2 [SAD in asthma patients]; Part 3 [MAD in healthy subjects under fasted conditions, with ...

Phase

0.13 miles

Learn More »

First Time in Human (FTIH) Study to Evaluate Safety Tolerability Immunogenicity Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3511294 Administered Subcutaneously (SC) in Subjects With Mild to Moderate Asthma

GSK3511294 is a humanized monoclonal antibody antagonist of Interleukin (IL)-5 which is known to block binding of IL-5 to the IL-5 receptor complex, causing a reduction in the circulating population of eosinophils. This is a single ascending dose FTIH study to investigate safety, tolerability, immunogenicity, pharmacokinetics (PK) and pharmacodynamics (PD) ...

Phase

0.13 miles

Learn More »

A Pharmacokinetic Study Comparing MB02 And US And EU Avastin In Healthy Male Volunteers

The primary PK parameters are Cmax and AUC(0-). The PK parameters for bevacizumab will be calculated using standard noncompartmental methods. An analysis of covariance model will be used to analyse the log-transformed primary PK parameters (AUC[0-].and Cmax) and AUC(0-t). The model will include a fixed effect for treatment and body ...

Phase

0.13 miles

Learn More »

A First Time in Human Study of PIN201104 in Healthy Volunteers and Patients With Asthma

The purpose of this study is to assess the safety, tolerability and pharmacokinetics of different single and repeat doses of PIN201104 in healthy volunteers and in patients with asthma.

Phase

1.03 miles

Learn More »

Single Ascending Dose Study of Lu AF76432 in Healthy Young Men

The purpose of this study is to investigate safety, tolerability and pharmacokinetics of the drug Lu AF76432 given as single oral ascending doses to healthy young men

Phase

1.03 miles

Learn More »

Safety Tolerability & Pharmacokinetics of LEVI-04 in Healthy Volunteers and Patients With Osteoarthritis Knee Pain

There will be 8 cohorts of 7 subjects each. Cohorts 1-3 will be composed of healthy volunteers. Cohorts 4-8 will be composed of osteoarthritis patients. Cohort 4 will be a bridging cohort; osteoarthritis patients in Cohort 4 will receive the same dose as the healthy volunteers in Cohort 3, if ...

Phase

3.59 miles

Learn More »

A Two Part Study to Assess Safety PK PD and Food Effect of Oral HTL0016878

This is a first in human single and multiple ascending dose study with the objective to evaluate safety, tolerability, PK, PD, and food effect of HTL0016878 in healthy younger and elderly subjects. Part 1 will assess single doses of HTL0016878 and Part 2 will assess multiple doses of HTL0016878. Part ...

Phase

3.59 miles

Learn More »

Assessment of Pharmacokinetics (PK) and Safety of M834 and Orencia in Healthy Subjects

The purpose of this study is assess the pharmacokinetics and safety of M834 and Orencia ® following administration of a single-dose in healthy volunteers.

Phase

3.59 miles

Learn More »