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Northwick Park, United Kingdom Clinical Trials

A listing of Northwick Park, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (8) clinical trials

A Pharmacokinetic Study Comparing MB02 And US And EU Avastin In Healthy Male Volunteers

The primary PK parameters are Cmax and AUC(0-). The PK parameters for bevacizumab will be calculated using standard noncompartmental methods. An analysis of covariance model will be used to analyse the log-transformed primary PK parameters (AUC[0-].and Cmax) and AUC(0-t). The model will include a fixed effect for treatment and body ...

Phase

0.13 miles

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The Colorectal Breath Analysis (COBRA) Study

Colorectal cancer is the 2nd most common cause of cancer death in the UK where survival rates are among the lowest in Europe. If diagnosed early survival may exceed 90%. The proposed breath test is a non-invasive investigation that can detect the presence of volatile organic compounds (VOCs) in breath ...

Phase N/A

0.13 miles

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An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers

The purpose of this study is to determine the efficacy and safety of investigational drug relatlimab plus nivolumab in combination with chemotherapy in participants with unresectable, untreated, locally advanced or metastatic gastric or GEJ cancer.

Phase

6.08 miles

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Weaning Algorithm for Mechanical VEntilation

Patients admitted to the intensive care unit typically receive invasive mechanical ventilatory support when they are critically ill. Whilst mechanical ventilation is a life-saving intervention, it can also lead to deleterious consequences and cause lung damage (known as ventilator-associated lung injury) if not implemented carefully. Hence, reducing the duration of ...

Phase N/A

7.34 miles

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A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is a randomized, open-label, parallel-group, multi-center trial in adult subjects with Relapsed or refractory (R/R) aggressive Non-Hodgkin lymphoma ...

Phase

8.72 miles

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Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study

In this proposed study we will use magnetic resonance imaging (MRI) of skeletal muscle to better delineate the natural history of intramuscular fat accumulation in Charcot Marie Tooth disease (CMT ) and investigate the use of muscle MRI and plasma neurofilament light chain (NEFL) levels as outcome measures in children ...

Phase N/A

9.23 miles

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A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

The purpose of this study is to evaluate the efficacy and safety of Lumasiran in Children and Adults with Primary Hyperoxaluria Type 1 (PH1).

Phase

9.32 miles

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Efficacy Safety & Utilisation of Nuwiq Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients

Octapharma's FVIII concentrates have been tested in clinical trials and registered for treatment of haemophilia A; however, as haemophilia A is a rare disease, the numbers of patients treated in studies so far are limited. For previously untreated patients (PUPs), who are typically young children, and for minimally treated patients ...

Phase N/A

9.32 miles

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