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Greater London, United Kingdom Clinical Trials

A listing of Greater London, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (11) clinical trials

A clinical research study called 'POINT' will evaluate if adding an oral study drug to Tecfidera® can have an effect on multiple sclerosis (MS) disease activity. In this study, patients with active relapsing MS will receive add-on therapy with ponesimod (a sphingosine 1-phosphate [S1P] receptor modulator) or placebo on top ...

Phase

2.59 miles

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Treatment-Resistant Depression Cohort in Europe

This TRD cohort study will collect critically important data from routine clinical practice in Europe which will further substantiate the understanding of TRD in European clinical practice, with the aim of improving guidance and informing the development of better treatment strategies for this medically important condition. All data recorded in ...

Phase N/A

2.7 miles

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Impact of Bariatric Surgery on Cardiorespiratory Function

Obesity is a growing problem worldwide and its prevention has become one of the leading priorities for the World Health Organisation. Obesity results from chronic imbalance between energy intake and energy expenditure. Although early prevention of obesity is preferable, surgical treatment is often required for severely obese people. Bariatric surgery ...

Phase N/A

3.44 miles

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Start or STop Anticoagulants Randomised Trial (SoSTART)

Bleeding within the skull, also known as brain haemorrhage, affects 3 million people in the world each year. One in five people who survive brain haemorrhage have an irregular heart rhythm called 'atrial fibrillation', which puts them at risk of stroke and other blood clots. Blood-thinning medicines, known as 'anticoagulant' ...

Phase

3.55 miles

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Basophil Activation Test to Diagnose Food Allergy

The BAT II Study is a cross-sectional diagnostic study in which children with suspected IgE-mediated allergy to foods (namely cow's milk, egg, sesame and cashew), as defined by a history of an immediate-type allergic reaction to a food or no history of food consumption or the presence of food-specific IgE ...

Phase N/A

4.76 miles

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Bile Acid Effects in Fetal Arrhythmia Study

Intrahepatic cholestasis of pregnancy (ICP) also known as obstetric cholestasis (OC) is a liver disorder unique to pregnancy that affects 0.5-1% of women in the UK. It typically presents in the third trimester of pregnancy with pruritus that can affect any part of the body, but is most commonly experienced ...

Phase N/A

4.76 miles

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A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.

This is a phase I/II open-label, multicenter study to evaluate the safety, tolerability, pharmacokinetics (PK) and antitumor activity of MEDI4736 in combination with olaparib in patients with advanced solid tumors, selected based on a rationale for response to olaparib. Patients will be poly (adenosine diphosphate-ribose) polymerase (PARP)-inhibitor and immunotherapy (IMT)-nave ...

Phase

5.1 miles

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Study in Huntington's Disease Patients Who Participated in Prior Investigational Studies of ISIS 443139

This study will test the safety, tolerability, pharmacokinetics and pharmacodynamics of IONIS-HTTRx administered intrathecally to adult patients with Huntington's Disease.

Phase

6.42 miles

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Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA)

The investigators aim is to establish a Spinal Muscular Atrophy (SMA) National Platform to improve UK standards of care, manage national and International clinical trials and facilitate translational research for this common neuromuscular disease. To achieve this purpose investigators will start to systematically collect longitudinal validated outcome measures for SMA ...

Phase N/A

6.48 miles

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HepCare: The Effectiveness of Community Based Interventions With Peer Support to Improve Case Detection Carry Out Pre-treatment Assessments and Assist Underserved Populations Through HCV Treatment

Introduction Hepatitis C infection is a major cause of chronic liver disease and death throughout the world1. Approximately 3% of the world's population is infected with hepatitis C virus (HCV)2. HCV is transmitted by blood and in the UK occurs primarily through injecting drug use. Chronically infected people are at ...

Phase N/A

6.59 miles

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